Results 71 to 80 of about 1,365,805 (285)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Estimation of parameter of proportion in Binomial Distribution Using Adjusted Prior Distribution
Historically, various methods were suggested for the estimation of Bernoulli and Binomial distributions parameter. One of the suggested methods is the Bayesian method, which is based on employing prior distribution.
h esfandiari +3 more
doaj
Optimal Allocation of the Sample in the Poisson Item Count Technique
Indirect methods of questioning are of utmost importance when dealing with sensitive questions. This paper refers to the new indirect method introduced by Tian et al.
Michał Bernardelli, Barbara Kowalczyk
doaj +1 more source
From marine park to future genomic observatory? Enhancing marine biodiversity assessments using a biocode approach [PDF]
Few tropical marine sites have been thoroughly characterised for their animal species, even though they constitute the largest proportion of multicellular diversity. A number of focused biodiversity sampling programmes have amassed immense collections to
Yin Cheong Aden Ip +7 more
doaj +3 more sources
Bayesian Joint Estimation of Binomial Proportions [PDF]
Testing the hypothesis H that k > 1 binomial parameters are equal and jointly estimating these parameters are related problems. A Bayesian argument can simultaneously answer these inference questions: to test the hypothesis H, the posterior probability λ = λ (H | x) of H given the experimental data x can be used; to estimate each binomial parameter,
openaire +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The proportion of false null hypotheses is a very important quantity in statistical modelling and inference based on the two-component mixture model and its extensions, and in control and estimation of the false discovery rate and false non-discovery ...
Chen, Xiongzhi
core +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Segment-level evaluation of the simulated aggregation test: US corn and soybean exploratory experiment [PDF]
An evaluation of the corn and soybean proportion-estimation accuracy and dot labeling accuracy of the Simulated Aggregation Test, U.S. Corn and Soybean Exploratory Experiment, is presented.
Davidson, S. A.
core +1 more source

