Results 311 to 320 of about 1,012,468 (372)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Estimating preclinical amyloid positivity: A case study transporting ADNI to ARIC. [PDF]

open access: yesAlzheimers Dement (N Y)
Stapp EK   +10 more
europepmc   +1 more source

Advancing image-based meta-analysis through systematic use of crowdsourced NeuroVault data. [PDF]

open access: yesSci Rep
Peraza JA   +6 more
europepmc   +1 more source

A Penalized Synthetic Control Estimator for Disaggregated Data

Journal of the American Statistical Association, 2021
Synthetic control methods are commonly applied in empirical research to estimate the effects of treatments or interventions on aggregate outcomes. A synthetic control estimator compares the outcome of a treated unit to the outcome of a weighted average ...
Alberto Abadie, Jérémy l'Hour
semanticscholar   +1 more source

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