Ascertainment Conditional Maximum Likelihood for Continuous Outcome Under Two-Phase Response-Selective Design. [PDF]
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Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
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Luqman M, Bhatti SH, Aydin D, Jamil M.
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Do Meta-Analyses of Total Hip Arthroplasty Produce Reliable Results? A Systematic Review and Meta-Epidemiological Study of Statistical Methods. [PDF]
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A Penalized Synthetic Control Estimator for Disaggregated Data
Journal of the American Statistical Association, 2021Synthetic control methods are commonly applied in empirical research to estimate the effects of treatments or interventions on aggregate outcomes. A synthetic control estimator compares the outcome of a treated unit to the outcome of a weighted average ...
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