Results 161 to 170 of about 163,518 (339)
Advanced Science, EarlyView.Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan +16 more
wiley +1 more source
Fecal Elimination of Hormones in Sheep and Cattle Treated with Synthetic Estrogens [PDF]
, 1956 Martin Stob
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Age, Sex, and Genetic Architecture of Human Gene Expression in EBV Transformed Cell Lines [PDF]
arXiv, 2009 Individual expression profiles from EBV transformed cell lines are an emerging resource for genomic investigation. In this study we characterize the effects of age, sex, and genetic variation on gene expression by surveying public datasets of such profiles.
arxiv
Topics of Interest in Women With Myeloproliferative Neoplasms
American Journal of Hematology, EarlyView.Women with MPN: life‐cycle phases, specific risks, and influencing factors. ABSTRACT Overview Sex and gender have emerged as central modifiers of disease biology, phenotype, and clinical outcomes in myeloproliferative neoplasms (MPNs). This review will uniquely highlight issues affecting women with MPN and articulate their relevant determinants ...
Natasha Szuber +2 more
wiley +1 more source
Data in Brief, 2019 Analysis of catechol estrogens (2 & 4 hydroxy-estrone and estradiol) has proven troublesome by liquid chromatography tandem mass spectrometry due to their low concentrations, short half-lives and temperature-labile nature.
Nina Denver +6 more
doaj
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini +8 more
wiley +1 more source
Potential New Expression Biomarkers for Anorexia Nervosa
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Anorexia nervosa (AN) is a psychiatric disorder with an estimated heritability of around 70%. Although the largest meta‐analysis of genome‐wide association studies on AN identified independent risk‐conferring loci for the disorder, the molecular mechanisms underlying the genetic basis of AN remain to be elucidated.
Camille Verebi +8 more
wiley +1 more source
Cancer Medicine, Volume 11, Issue 24, Page 4767-4783, December 2022., 2022 1. In this study, we observed that mucinous breast cancer with metastatic lymph nodes have a worse prognosis and identified tumor size, grade and age as independent risk factors of lymph node metastasis. 2. we constructed a nomogram with factors of tumor size, grade, age and developed a risk classification system for predicting the risk of lymph node ...
Shuang‐Ling Wu +4 more
wiley +1 more source
Detection of Estrogenic Substances in Alfalfa and Clover Hays Fed to Fattening Lambs [PDF]
, 1953 Edmund W. Cheng +4 more
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Mitosis, Cytoskeleton Regulation, and Drug Resistance in Receptor Triple Negative Breast Cancer [PDF]
arXivDuring cell division, the receptor triple-negative MDA-MB-231 mitotic spindles are the largest in comparison to other BC cell lines. Many of the MDA-MB-231 spindles exhibit rapid lateral twisting during metaphase, which remains unaffected by knockdown of the oncogene Myc and treatment with inhibitors of the serine/threonine-protein kinase B-Raf and the
arxiv