Results 211 to 220 of about 226,665 (388)
Studies on the Estrogen-sensitive Enzyme System from Placenta
, 1959 Vincent P. Hollander +2 more
openalex +1 more source
Advanced NanoBiomed Research, EarlyView.This study demonstrates that combination of phosphosensitizer‐conjugated chitosan nanoparticles and ferroptosis inducer RSL3 increases cell death in mesenchymal breast cancer cells. Data suggests that this is attributed to variations in ferroptosis‐related protein expression, lipid peroxydation and mitochondrial function.
Marek Feith +10 more
wiley +1 more source
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background Photodynamic therapy (PDT) is a minimally invasive, clinically approved therapy with numerous advantages over other mainstream cancer therapies. 5‐aminolevulinic acid (5‐ALA)‐PDT is of particular interest, as it uses the photosensitiser PpIX, naturally produced in the heme pathway, following 5‐ALA administration.
Maria Mastrangelopoulou +7 more
wiley +1 more source
Molecular and cellular paradigms of multidrug resistance in cancer
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya +6 more
wiley +1 more source
Sex‐Based Disparities in Sinonasal Outcomes: A Population‐Based Study
International Forum of Allergy &Rhinology, EarlyView.
Victoria S. Lee +5 more
wiley +1 more source
Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology
Angewandte Chemie International Edition, Accepted Article.Targeted protein degradation (TPD) has emerged as a transformative therapeutic strategy for eliminating disease‐associated proteins, with relevance across disorders ranging from cancer to neurodegeneration. Since its inception nearly two decades ago, TPD has attracted strong academic and commercial interest, with multiple candidates advancing into ...
Andrew G. Baker +3 more
wiley +1 more source
Role of eIF4A1 in triple‐negative breast cancer stem‐like cell‐mediated drug resistance
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract In cap‐dependent translation, the eukaryotic translation initiation factor 4A (eIF4A1) is an mRNA helicase is involved in unwinding of the secondary structure, such as the stem‐loops, at the 5′‐leader regions of the key oncogenic mRNAs. This facilitates ribosomal scanning and translation of the oncogenic mRNAs.
Dayanidhi Raman, Amit K. Tiwari
wiley +1 more source
Separation of Human Placental Estrogen-sensitive Transhydrogenase from Estradiol-17β Dehydrogenase
, 1959 Dwain D. Hagerman, Claude A. Villee
openalex +1 more source
Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade +2 more
wiley +1 more source