Results 1 to 10 of about 46 (43)

Eating disorders in young patients with neurofibromatosis type 1

Journal of Paediatrics and Child Health, Volume 59, Issue 5, Page 723-728, May 2023., 2023
Aim We describe the association of neurofibromatosis type 1 (NF1) and feeding and eating disorders (FED) in five patients admitted to our third level centre for both FED and NF1. Methods Case series of five adolescent females with NF1 treated for FED. Results We collected data from five patients with NF1 aged between 14 and 22 years, all females.
Francesca Chiavarino, Jacopo Pruccoli, Ilaria Cecconi, Nicolò Vancini, Duccio M Cordelli, Antonia Parmeggiani   +5 more
wiley   +1 more source

Extrusion 3D printing of a multiphase collagen‐based material: An optimized strategy to obtain biomimetic scaffolds with high shape fidelity

Journal of Applied Polymer Science, Volume 140, Issue 10, March 10, 2023., 2023
A multiphase biomaterial ink combining type‐I‐collagen with nano‐sized mesoporous bioactive glasses and nanohydroxyapatite was successfully designed to mimic the natural composition of bone. Based on rheological data and computational‐fluid‐dynamic models, the printing set‐up was optimized to obtain scaffolds characterized by high printing fidelity and
Giorgia Montalbano, Andrea Roberto Calore, Chiara Vitale‐Brovarone   +2 more
wiley   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, Volume 26, Issue 7, July 2026.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

In Silico Drug Repositioning Identifies SYK Kinase Inhibitors as Potential Neuroprotective Agents for Ataxia–Telangiectasia

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
Repositioning of vemurafenib and palbociclib as spleen tyrosine kinase inhibitors for the treatment of neuroinflammation in Ataxia–Telangiectasia. ABSTRACT Ataxia–Telangiectasia (AT) is a rare neurodegenerative disorder characterized by progressive neuronal loss and chronic neuroinflammation.
Alessia Romano, Rocco Buccheri, Chiara Zagni, Antonio Rescifina   +3 more
wiley   +1 more source

Associations of PYY, GLP‐1 and LEAP2 with changes in feeding‐related cognition, body weight and glucose homeostasis after bariatric surgery in non‐diabetic women

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Roux‐en‐Y gastric bypass (RYGB) is an effective surgical intervention for severe obesity, but the role of gastrointestinal hormones in its benefits remains unclear. We examined longitudinal pre‐to‐post‐meal gastrointestinal hormone changes and their relationships with glucose homeostasis and feeding‐related cognitive responses in women ...
María F. Andreoli, Pablo N. De Francesco, Wei Zhou, Olga E. Titova, Ahmed Alsehli, Robert Fredriksson, Magnus Sundbom, Mario Perello, Helgi B. Schiöth   +8 more
wiley   +1 more source

Tolcapone Interferes With Key Pathological Features in Alzheimer’s Disease

Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
Tolcapone, a clinically approved drug for the treatment of Parkinson’s disease as an adjunct therapy, has recently emerged as a potential modulator of amyloid‐β aggregation and toxicity, which are hallmark features of Alzheimer’s disease and are also involved in ocular neurodegenerative disorders, including glaucoma and age‐related macular degeneration.
Alessia Distefano, Damiano Calcagno, Giuseppe Grasso, Olivier Monasson, Elisa Peroni, Valentina Oliveri, Massimiliano F. Peana   +6 more
wiley   +1 more source

Abstracts

, 2023
Molecular Oncology, Volume 17, Issue S1, Page 1-597, June 2023.
wiley   +1 more source

Broad‐Spectrum Diffusion Coefficient Measurements via Surface Plasmon Resonance: From Thermodynamics to Protein Conformational Disorders

ChemPhysChem, Volume 26, Issue 16, August 23, 2025.
Recent advancements in surface plasmon resonance protocols and simulations have enhanced the measurement and prediction of diffusion coefficients (D) for chemical species in microfluidic channels. These developments enable precise determination of D values for molecules ranging from a few angstroms to nanometric aggregates, facilitating detailed ...
Giuseppe Stefano Basile, Damiano Calcagno, Nunzio Tuccitto, Diego Sbardella, Giuseppe Grasso   +4 more
wiley   +1 more source

VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease

Aging Cell, Volume 24, Issue 7, July 2025.
Amyloid‐β (Aβ) oligomers affect VDAC1 electrophysiology and the physiological metabolic cross‐talk between cytosol and mitochondria. The use of a small, synthetic VDAC1‐antagonist peptide, derived from hexokinase, restores mitochondrial functionality, and respiration in cellular models of Alzheimer's disease. ABSTRACT Mitochondrial dysfunction has been
Fabrizio Cavallaro, Stefano Conti Nibali, Salvatore Antonio Maria Cubisino, Pietro Caruso, Stefania Zimbone, Iolanda Rita Infantino, Simona Reina, Vito De Pinto, Angela Messina, Maria Laura Giuffrida, Andrea Magrì   +10 more
wiley   +1 more source

Valproate discontinuation in girls and women of childbearing age with epilepsy: An Italian multicenter retrospective study on prescribing patterns and outcomes

Epilepsia, Volume 66, Issue 5, Page 1529-1539, May 2025.
Abstract Objective This study aimed to identify prescribing behaviors in women of childbearing potential (WOCP) with epilepsy already taking valproate (VPA), and to investigate the relationship between VPA maintenance, substitution, reduction, or withdrawal as part of polytherapy, and seizure worsening or relapse.
Roberta Esposto, Giovanni Falcicchio, Elena Zambrelli, Emanuele Cerulli Irelli, Giulia Monti, Federica Ranzato, Loretta Giuliano, Angela La Neve, Carlo Adrea Galimberti, Laura Maria Beatrice Belotti, Katherine Turner, Cecilia Catania, Diana Polo, Valeria Todaro, Francesca Bisulli, Barbara Mostacci, Appendix A: Epilepsy and Gender Commission of the LICE (Italian chapter of the ILAE)   +16 more
wiley   +1 more source