Results 91 to 100 of about 49,940 (198)
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases
Periodontology 2000, EarlyView.Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva +2 more
wiley +1 more source
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Experimental Physiology, EarlyView.Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 684-691, September 2026.Biologic therapies are a major and growing driver of pharmaceutical expenditure globally, with tumor necrosis factor (TNF) inhibitors among the most widely used and costly biologics. In Australia, these therapies are funded through the Pharmaceutical Benefits Scheme (PBS), where biosimilars offer lower cost alternatives; however, the long‐term public ...
Chin Hang Yiu +4 more
wiley +1 more source
Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit
The Laryngoscope, Volume 136, Issue 9, Page 3980-3989, September 2026.This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann +4 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Liya Sisay Getachew +34 more
wiley +1 more source
Etanercept in the Treatment of Vitiligo
Dermatology, 2007 Rigopoulos, Dimitris +5 more
openaire +3 more sources
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective Rehabilitation is rarely integrated into routine rheumatology care, despite high rates of functional limitation in adults with rheumatoid arthritis (RA). The Preserving Valued Activities in Life (PREVAIL) model of care proposes a function‐focused screening survey administered during routine rheumatology visits to guide referrals to ...
Louise M. Thoma +5 more
wiley +1 more source
Real‐World Treatment Patterns in Rheumatoid Arthritis–Associated Interstitial Lung Disease
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective We evaluated real‐world treatment patterns in rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) within the Veterans Health Administration (VA). Methods We performed a cohort study of RA‐ILD treatment patterns in the VA between 2006 and 2021.
Justin T. Dunn +12 more
wiley +1 more source
Etanercept (Enbrel®) alternative storage at ambient temperature
Clinical Pharmacology: Advances and Applications, 2017 Edel Shannon,1 Joanne Daffy,2 Heather Jones,3 Andrea Paulson,4 Steven M Vicik5 1Global Chemistry, Manufacturing, and Controls Regulatory, 2Contract Operations Quality Assurance, Pfizer Ireland Pharmaceuticals, Clondalkin, Dublin, Ireland; 3Medical ...
Shannon E +4 more
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