Results 21 to 30 of about 49,940 (198)

TNF-α antagonist attenuates systemic lipopolysaccharide-induced brain white matter injury in neonatal rats

open access: yesBMC Neuroscience, 2019
Background Systemic inflammation is an important risk factor for neurodevelopmental impairments in preterm infants. Premyelinating oligodendrocytes are main building blocks of white matter in preterm infants and vulnerable to oxidative stress and ...
Seung Han Shin   +3 more
doaj   +1 more source

A case of postoperative nasopharyngeal reflux associated with retropharyngeal lymphangioma in newborn infant [PDF]

open access: yesKorean Journal of Pediatrics, 2010
Tumor necrosis factor-?#6184;TNF-?#6752;is a major proinflammatory cytokine involved in the pathophysiology of juvenile rheumatoid arthritis. Etanercept is an effective inhibitor of TNF-?#6177;nd has shown a beneficial effect in patients with JRA ...
Ah Reum Kwon   +3 more
doaj   +1 more source

Fecal microbiota in children with juvenile idiopathic arthritis treated with methotrexate or etanercept

open access: yesPediatric Rheumatology Online Journal, 2021
Background Alterations in the composition of the fecal microbiota in children with juvenile idiopathic arthritis (JIA) have been observed in several studies, but it has not been determined whether the standard treatment for JIA changes the composition or
Anders Öman   +3 more
doaj   +1 more source

Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. [PDF]

open access: yesPLoS ONE, 2012
Acute liver failure (ALF) due to ischemic or toxic liver injury is a clinical condition that results from massive loss of hepatocytes and may lead to hepatic encephalopathy (HE), a serious neuropsychiatric complication.
Anne Chastre   +5 more
doaj   +1 more source

A randomized controlled trial of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To evaluate the effectiveness of etanercept in the treatment of refractory recurrent spontaneous abortion with innate immune disorders. Materials and methods: A randomized controlled trial in patients with refractory innate immune RSA was ...
Jinhua Fu, Lin Li, Lijuan Qi, Long Zhao
doaj   +1 more source

Biologic TNF-α inhibitors reduce microgliosis, neuronal loss, and tau phosphorylation in a transgenic mouse model of tauopathy

open access: yesJournal of Neuroinflammation, 2021
Background Tumor necrosis factor-α (TNF-α) plays a central role in Alzheimer’s disease (AD) pathology, making biologic TNF-α inhibitors (TNFIs), including etanercept, viable therapeutics for AD.
Weijun Ou   +10 more
doaj   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker   +14 more
wiley   +1 more source

Evaluation of Efficacy and Safety of Etanercept and Etanercept + Methotrexate Therapy in Patients with Juvenile Idiopathic Arthritis without Systemic Manifestations

open access: yesВопросы современной педиатрии, 2016
Background: At present, it is urgent to find ways to overcome the inefficiency of and intolerance to the methotrexate therapy in patients with juvenile idiopathic arthritis (JIA).
T. M. Bzarova   +10 more
doaj   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai   +7 more
wiley   +1 more source

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