Results 81 to 90 of about 13,081,117 (322)

How a modern business could respond to the phishing attack challenges [PDF]

open access: yesTehnika, 2017
The majority of public and private enterprises as well as the entire society are getting dependable on cyber technologies. As it's known - cyber would deal with computers, internet and mobile devices being used through our everyday life's and work's ...
Đekić Milica D.
doaj   +1 more source

Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance.

open access: yesJournal of Clinical Lipidology, 2016
BACKGROUND ETC-1002 is an oral, once-daily, first-in-class medication being developed to treat hypercholesterolemia. OBJECTIVES To compare 2 doses of ETC-1002, alone or combined with ezetimibe 10 mg (EZE), vs EZE monotherapy for lowering low-density ...
P. Thompson   +7 more
semanticscholar   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers   +7 more
wiley   +1 more source

Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase

open access: yesCurrent Atherosclerosis Reports, 2016
Bempedoic acid (ETC-1002), a novel therapeutic approach for low-density lipoprotein cholesterol (LDL-C) lowering, inhibits ATP citrate lyase (ACL), an enzyme involved in fatty acid and cholesterol synthesis.
Ozlem Bilen, C. Ballantyne
semanticscholar   +1 more source

Flavor-Changing Processes in Extended Technicolor

open access: yes, 2004
We analyze constraints on a class of extended technicolor (ETC) models from neutral flavor-changing processes induced by (dimension-six) four-fermion operators. The ETC gauge group is taken to commute with the standard-model gauge group.
D. Becirevic   +13 more
core   +1 more source

Performance Characteristics of Anti–Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick   +6 more
wiley   +1 more source

Effect of ETC-1002 on Serum Low-Density Lipoprotein Cholesterol in Hypercholesterolemic Patients Receiving Statin Therapy.

open access: yesAmerican Journal of Cardiology, 2016
ETC-1002 is an oral, once-daily medication that inhibits adenosine triphosphate citrate lyase, an enzyme upstream of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, to reduce cholesterol biosynthesis.
C. Ballantyne   +6 more
semanticscholar   +1 more source

Results on improved KS dynamical configurations: spectrum, decay constants, etc

open access: yes, 2003
The MILC Collaboration has been producing ensembles of lattice configurations with three dynamical flavors for the past few years. There are now results for three lattice spacings for a variety of light and strange quark masses, ranging down to $m_l=0.1 ...
Aubin   +18 more
core   +2 more sources

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