Results 141 to 150 of about 189,870 (274)

Microneedle delivery systems for vaccines and immunotherapy

open access: yesSmart Molecules, EarlyView.
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia   +5 more
wiley   +1 more source

Air‐Stable Lithiation of MoS2 for Direct‐Bandgap Multilayers

open access: yesSmall Science, EarlyView.
This atomic‐force‐microscopy‐guided ionic modulation enables rewritable, air‐stable direct‐bandgap semiconductor fabrication of multilayer MoS2 without inducing metallic phase transition, unlocking monolayer‐like optoelectronic functionalities of multilayer MoS2.
Qi Fu   +11 more
wiley   +1 more source

Fabrication of Microneedles by Pulsating In Situ Dried Electrostretching for Transdermal Drug Delivery

open access: yesSmall Methods, EarlyView.
The pulsating in situ dried electrostretching (PIDES) technique offers a novel approach to microneedles fabrication for transdermal drug delivery utilizing electrohydrodynamic principles. PIDES is capable of fabricating biodegradable polymeric microneedles with geometric and mechanical properties suitable for skin penetration. Drug loading and in vitro
Ngoc Luan Mai   +9 more
wiley   +1 more source

StableTi3C2Tx MXene Ink Formulation and High‐Resolution Aerosol Jet Printing for High‐Performance MXene Supercapacitors

open access: yesSmall Methods, EarlyView.
A novel additive free Ti3C2Tx MXene ink is formulated for aerosol jet printing, enabling stable, high‐resolution patterning. The printed micro‐supercapacitors deliver strong electrochemical performance, illustrating the use of additive manufacturing for compact energy storage in wearable and distributed electronics.
Fereshteh Rajabi Kouchi   +13 more
wiley   +1 more source

Conducting Polymer Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Brain Imaging

open access: yesAdvanced Functional Materials, Volume 35, Issue 24, June 19, 2025.
A flexible micro‐electrocorticography array with PEDOT:SS electrodes is shown to be compatible with ultra‐high magnetic field MRI up to 9.4 T. Multimodal brain monitoring is demonstrated by performing simultaneous blood oxygen level‐dependent functional MRI in parallel with electrophysiology.
Sagnik Middya   +7 more
wiley   +1 more source

Materials, Structure, and Interface of Stretchable Interconnects for Wearable Bioelectronics

open access: yesAdvanced Materials, Volume 37, Issue 23, June 12, 2025.
Stretchable interconnects are one of the fundamental components in achieving robust wearable devices, but their importance is often overlooked. This review highlights their importance and provides insightful information on various materials, configurations, and manufacturing approaches being studied for interconnects.
Yue Li   +3 more
wiley   +1 more source

Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications

open access: yesAdvanced Materials, Volume 37, Issue 24, June 19, 2025.
A customizable and scalable approach to fabricate flexible 3D kirigami microelectrode arrays (MEAs) featuring up to 128 shanks, including surface and penetrating electrodes designed to interact with the 3D space of neural tissue, is presented. The 3D kirigami MEAs are successfully deployed in several neural applications, both in vitro and in vivo, and ...
Marie Jung   +10 more
wiley   +1 more source

A Flexible‐Substrate 5‐µm‐Diameter Needle Electrode: Minimizing Neuronal Death and Enabling Year‐Long Neural Recording

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 11, June 9, 2025.
An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki   +6 more
wiley   +1 more source

Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design

open access: yesAdvanced Materials Technologies, Volume 10, Issue 11, June 5, 2025.
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo   +6 more
wiley   +1 more source

Nanotherapy for Neural Retinal Regeneration

open access: yesAdvanced Science, Volume 12, Issue 24, June 26, 2025.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu   +11 more
wiley   +1 more source

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