Results 181 to 190 of about 348,478 (301)

Titanium Dioxide Nanoparticles-Induced Genotoxic Effects in Mosquito Culex quinquefaciatus. [PDF]

open access: yesToxics
Saini A   +7 more
europepmc   +1 more source

Uncharted

open access: yes
Journal of Hospital Medicine, EarlyView.
Julie Eckelbarger
wiley   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu   +4 more
wiley   +1 more source

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang   +5 more
wiley   +1 more source

Simultaneous Assessment of Skeletal Muscle Energetics and Blood Flow During Dynamic Exercise by Interleaved 31P‐MRS/1H‐MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To simultaneously measure skeletal muscle energetics and blood flow (BF) before, during, and after dynamic plantar flexion exercise (PFE). Methods Non‐localized pulse‐acquire phosphorus‐31 magnetic resonance spectroscopy (31P MRS) and phase contrast flow magnetic resonance imaging (1H MRI) using golden‐angle rotated spiral readouts ...
T. Jake Samuel   +6 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

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