Results 31 to 40 of about 143,404 (302)

Eternal universes

open access: yesPhysical Review D
We consider the possibility of a past and future eternal universe, constructing geodesically complete inflating, loitering, and bouncing spacetimes. We identify the constraints energy conditions that general relativity place on the building of eternal cosmological models.
Damien A. Easson, Joseph E. Lesnefsky
openaire   +2 more sources

Time in the ontology of Cornelius Castoriadis [PDF]

open access: yes, 2017
We can locate the problematic of time within three philosophical questions, which respectively designate three central areas of philosophical reflection and contemplation. These are: 1) The ontological question, i.e.
Schismenos, Alexandros
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Three Interpretations of God’s Eternity;Mulla Sadra’s Transcendent Wisdom’s Point of View [PDF]

open access: yesحکمت معاصر, 2014
In this article, through a descriptive-analytical method, the viewpoint of Mulla Sadra, the founder of transcendent wisdom, on God’s eternity, has been explained and studied.
Mehdi Zamani
doaj  

Kalam cosmological argument [PDF]

open access: yesFilozofija i Društvo, 2011
In this paper it will be presented polemics about kalam cosmological argument developed in medieval islamic theology and philosophy. Main moments of that polemics was presented for a centuries earlier in Philoponus criticism of Aristotle’s thesis that
Đurić Drago
doaj   +1 more source

Eternal God: Divine Atemporality in Thomas Aquinas [PDF]

open access: yes, 2014
The recent trend among many philosophers of religion has been to interpret divine eternity as an everlasting temporality in which an omnitemporal God exists in and throughout the whole of time.
Boyer, John H.
core  

Francisco Suárez on Eternal Truths, Eternal Essences, and Extrinsic Being [PDF]

open access: yes, 2017
It is necessarily true that water is H2O, but it is a contingent fact that there is any water at all. Water therefore seems ill suited to ground the necessary truth that water is H2O.
Embry, Brian
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

THEORY IDEAS OF PLATO AS A DOCTRINE ABOUT EXISTENCE OUTSIDE TIME AND SPASE

open access: yesJuvenis Scientia, 2019
This article investigates Plato's theory postulating permanence, eternity and perfection of ideas. The results of research show originality of the method that is chosen by Plato to achieve his goal.
Sizov R.S., Vorobev D.V.
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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