Results 271 to 280 of about 186,980 (339)

NPR1 Promotes Lipid Droplet Lipolysis to Enhance Mitochondrial Oxidative Phosphorylation and Fuel Gastric Cancer Metastasis

Advanced Science, EarlyView.
NPR1 induces lipolysis of stored lipid droplet and enhances mitochondrial oxidative phosphorylation to fuel gastric cancer metastasis. Specifically, NPR1‐mediated activation of PKG directly phosphorylates and activates HSL at Ser855 and Ser951, thereby driving lipolytic processes.
Huafeng Fu, Jie Zhang, Hengxing Chen, Haobin Hou, Huanjie Chen, Rongman Xie, Yanlei Chen, Jian Zhang, Dehua Liu, Leping Yan, Rui L. Reis, Joaquim M. Oliveira, Yulong He, Li Zhong, Qinbo Cai, Dongjie Yang   +15 more
wiley   +1 more source

Comparing the financial, energy and time costs of different food and stove combinations in Nairobi using controlled cooking tests and longitudinal fuel price data. [PDF]

UCL Open Environ
Perros T, O'Keefe M, Mwitari J, Gichane L, Puzzolo E, Pope D.   +5 more
europepmc   +1 more source

In Situ Light‐Modulation of Capacity and Impedance in Lithium‐Ion Batteries

Advanced Science, EarlyView.
This study introduces a dynamic light‐controlled modulation (DLCM) anode for LIBs using CdS alignments and light‐sensitive graphene, effective across UV to visible light. The developed DLCM anode exhibits a remarkable maximum capacity of 430 mAh g−1 when subjected to UV light illumination, surpassing the capacity observed in the absence of illumination,
Hong Yin, Xiangxiang Yu, Yucan Zhu, Zhaohui Hou, Joao Cunha, Zhenxing Liang, Zhipeng Yu   +6 more
wiley   +1 more source

Generation of Novel Fuels Optimized for High-Knock Resistance with a Long Short-Term Memory Model. [PDF]

Energy Fuels
Anufriev S, Hellier P, Ladommatos N.
europepmc   +1 more source

Physical and Chemical Characterization of Fuel Ethanol Coproducts Relevant to Value‐Added Uses

, 2010
Rumela Bhadra, Kasiviswanathan Muthukumarappan, Kurt A. Rosentrater   +2 more
openalex   +2 more sources

Lipid Droplet‐Organized MDM2‐Mediated P53 Degradation: A Metabolic Switch Governing Diet‐Driven Tumor Progression

Advanced Science, EarlyView.
Tumor‐associated TP53 inactivation correlates with lipid droplet (LD) accumulation. High‐fat diets drive Cyb5r3‐Myh9‐mediated p53 enrichment on LD surfaces, accelerating its degradation while upregulating LD‐promoting factor CD36 expression to establish a feed‐forward loop. LD suppression or dietary intervention restores p53 and inhibits tumorigenesis,
Haiyang Liu, Lin Jing, Yixin Li, Jinxing Zhou, Xiaohui Cui, Sen Li, Shijie Yang, Fangming Kan, Junfeng Du, Wentao Zhong, Sheng Yu, Ning Wang, Xing Jia, Junhui Li, Pan Nie, Zhenzhong Chen, Ying Han, Lingxi Jiang, Xiyun Yan, Hongxia Duan, Baiyong Shen   +20 more
wiley   +1 more source

Longitudinal Hierarchy Co3O4 Mesocrystals with High-dense Exposure Facets and Anisotropic Interfaces for Direct-Ethanol Fuel Cells. [PDF]

Sci Rep, 2016
Hassen D, El-Safty SA, Tsuchiya K, Chatterjee A, Elmarakbi A, Shenashen MA, Sakai M.   +6 more
europepmc   +1 more source

System dynamics modeling of corn ethanol as a bio transportation fuel in the United States

, 2010
Deogratias Kibira, Guodong Shao, Stephen Nowak   +2 more
openalex   +1 more source

DNase I‐Mediated Chemotactic Nanoparticles for NETs Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke

Advanced Science, EarlyView.
The neutrophil extracellular traps (NETs) play an important role in reperfusion injury in ischemic stroke. Here, considering the unique vascular localization of NETs, a DNase I‐mediated NETs‐targeting nanoparticle is developed to integrate the catalytic and chemotactic functions of DNase I and achieve the synergistic regulation of the internal and ...
Tongyu Zhang, Peixin Liu, Wenru Shen, Chao Li, Zhenhao Zhao, Yuxing Wu, Tao Sun, Chen Jiang   +7 more
wiley   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source