Results 201 to 210 of about 12,704 (308)

Radical cyclization in heterocycle synthesis. Part 14. A simple and effective preparation of cyclic oxime ethers by photochemical radical addition–cyclization of acyclic oxime ethers

ARKIVOC, 2003
Okiko Miyata, Rina Yamanaka, Masafumi Ueda, Takeaki Naito   +3 more
doaj   +1 more source

Catalytic Enantioselective Cross-Nucleophile Coupling via Valence Tautomerism. [PDF]

J Am Chem Soc
Zhang Z, Khosravi A, Shah JA, Quirion KP, Yachuw SC, Poore AT, Tian S, Liu P, Ngai MY.   +8 more
europepmc   +1 more source

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Base-Promoted Conversion of Propargylic Alcohols to 1,3-Enynes. [PDF]

Org Lett
Delattre M, Wiegand M, Wang Q, Zhu J.
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Three-Component Catalytic Amino Etherification of Alkenes: Enabled by Silyl Ether-Promoted C-O Coupling. [PDF]

ACS Catal
Feng G, Nguyen AL, Wang Q.
europepmc   +1 more source

Machine‐Learning‐Enhanced Printed Vertical Magnetoresistive Sensors for Transparent, Flexible, Multimodal Interactive Magnetoelectronics

Advanced Science, EarlyView.
This study presents printed magnetoresistive sensors with a vertically aligned architecture that enables high optical transparency and mechanical flexibility. By integrating deep learning for the analysis of complex spatiotemporal signal patterns, the system further achieves intelligent multimodal interaction capabilities.
Rui Xu, Guannan Mu, Oleksandr V. Pylypovskyi, Qihao Zhang, Rico Illing, René Hübner, Ran He, Andreas Knüpfer, Sebastian Lehmann, Olha Bezsmertna, Kornelius Nielsch, Denys Makarov   +11 more
wiley   +1 more source

Impact of Electrolyte Formulation on the Phase Behavior and Interphase Formation of Sb/Graphite Electrodes for K‐Ion Batteries

Advanced Science, EarlyView.
Electrolyte formulation is shown to govern both interphase chemistry and bulk phase evolution in Sb/graphite anodes for potassium‐ion batteries. A diglyme‐based localized high‐concentration electrolyte promotes a thin inorganic‐rich interphase, suppresses deep graphite potassiation, limits electrode swelling, and stabilizes amorphous KxSb formation ...
Ezzoubair Bendadesse, Max Wacha, Zeynep Erdol, Yanan Sun, Carsten Prinz, Mirko Boin, Manuela Klaus, Tatiana Mishurova, Till Wolfram, Jürgen Janek, Philipp Adelhelm   +10 more
wiley   +1 more source

Electrochemical Chlorine Shuttle from PVC Waste to Vinyl Ether Acceptors for the Synthesis of Biodegradable Polyester Precursors. [PDF]

Adv Mater
Becker S, Wördehoff D, Weis D, Horsinka S, Waldvogel SR, Besenius P.   +5 more
europepmc   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source