Results 181 to 190 of about 7,802,095 (352)

A causal model of leader ethical behavior and radical innovation: the mediating effect of leader identification and the moderating effect of promotion focus. [PDF]

Front Psychol
Zhu L, Wang L, Jin X.
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

5. Social Darwinism Reconsidered

, 1958
Although the contemporary reaction to the implications of evolution was generally one of long-term optimism, an antithetical reaction did exist. Seen in stark terms, evolutionary theories were depressing to those who, on religious or humanitarian grounds,
Bloom, Robert L., Crapster, Basil L., Dunkelberger, Harold L., Glatfelter, Charles H., Mara, Richard T., Richardson, Norman E., Schubart, W. Richard   +6 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Assessing ethical behavior and self-control in elite ultimate championships: a cross-sectional study using the spirit of the game scoring system. [PDF]

Front Sports Act Living
Amoroso JP, Coelho L, Boulton RA, González-Toro CM, Costa F, Christodoulides E, Cools W, Dudley D, Moore JE, Furtado GE, Cheng MY, Calmeiro L.   +11 more
europepmc   +1 more source

Spot on for liars! How public scrutiny influences ethical behavior. [PDF]

PLoS One, 2017
Ostermaier A, Uhl M.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Income tax evasion in a society of heterogeneous agents: Evidence from an agent-based model [PDF]

We analyze the evolution and extent of income tax evasion under alternative governmental policies in an agent-based model with heterogeneous agents. A novel aspect of our modeling is the use of an exponential utility function, which allows us to assume ...
Hokamp, Sascha, Pickhardt, Michael
core  

Understanding ethical purchasing behavior: Validation of an enhanced stage model of ethical behavior

Journal of Retailing and Consumer Services, 2019
Henrike Andersch, Christian Arnold, Ann-Kathrin Seemann, Jörg Lindenmeier   +3 more
semanticscholar   +1 more source