Results 41 to 50 of about 327,382 (310)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Perception of and attitude toward ethical issues among Korean occupational physicians
Annals of Occupational and Environmental Medicine, 2017 Background Occupational physicians (OPs) have complex relationships with employees, employers, and the general public. OPs may have simultaneous obligations towards third parties, which can lead to variable conflicts of interests.
Junghye Choi +11 more
doaj +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
ArbitrerThis study assesses the awareness and understanding of the Literature, Publishing and Translation Commission (LPTC) / Saudi Arabian Translation Association (SATA) code of ethics amongst translators in Saudi Arabia, along with their degree of compliance ...
Eisa Ahmad S Asiri +2 more
doaj +1 more source
THE ROLE OF THE CODE OF ETHICS IN THE CONTEMPORARY FIRMS ACTIVITY [PDF]
Annals of the University of Petrosani: Economics, 2010 Nothing is eternal, except changes. This statement characterizes the contemporary world, as succinctly and correctly as possible. The field of economic affairs, strongly marked by the effects of the economic globalization process development, by the ...
ANDREEA GANGONE, CAMELIA CHIRILA
doaj
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Human resources managers as custodians of the King III code
South African Journal of Economic and Management Sciences, 2015 The objective of this research was to perform an exploratory study on the knowledge and understanding of the King III code among Human Resources (HR) managers in South African companies.
Frank de Beer, Daniel Hercules du Toit
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Evolución histórica de la aplicación de la ética en el mundo del fútbol
Vergentis. Revista de Investigación de la Cátedra Internacional Conjunta Inocencio III, 2020 This article is of particular objective to see how the competent organizations regulate some matters of great importance such as ethics and integrity in the world of football.
Cesar A. Giner Alegría +1 more
doaj