Real‐World Safety of Concomitant Colchicine and Statin Therapy
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan +5 more
wiley +1 more source
Experiences and challenges of healthcare professionals in oncological surgery during the COVID-19 pandemic: A qualitative study. [PDF]
Stengler AL +3 more
europepmc +1 more source
Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen +24 more
wiley +1 more source
Delineating a Spectrum of Physician Participation in Medical Aid in Dying: A Qualitative Exploration. [PDF]
Albright K +6 more
europepmc +1 more source
Objective Estimating the incidence and prevalence of symptomatic hand osteoarthritis (OA) in the Dutch population using a validated algorithm that integrates free‐text data from primary care electronic health records (EHRs). Methods This retrospective cohort study used the Integrated Primary Care Information database, including EHRs from approximately ...
Onur Kaya +7 more
wiley +1 more source
A de-identified inpatient clinical pathway dataset integrating ICD-10 diagnoses, ICD-9-CM procedures, Indonesian Case-Based Groups (INA-CBG), and length of stay for healthcare analytics. [PDF]
Nugroho S, Ginardi RVH, Purnama IKE.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Bioethics and Medical Litigation in France: An Exploratory Study. [PDF]
Nader R +4 more
europepmc +1 more source
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti +16 more
wiley +1 more source
Variation in Primary Care Diagnostic Codes Used to Define Health Conditions for Research: Comparison of 45 Health Data Research UK Phenotype Library Codelists for Eight Health Conditions. [PDF]
Kelly B +6 more
europepmc +1 more source

