Results 151 to 160 of about 8,890,530 (360)

ON THE ISSUE OF FORMING AN ETHICAL POSITION FUTURE LAWYER

open access: diamond, 2023
I.D. Belonovskaya, YU.S. BARABANOVA
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Towards a Moderate Stance on Human Enhancement

open access: yesHumana.Mente: Journal of Philosophical Studies, 2014
In this essay, we argue against radical ethical views about human enhancement that either dismiss or endorse it tout court. Instead, we advocate the moderate stance that issues of enhancement should be examined with an open mind and on a case-by-case ...
Nikil Mukerji, Julian Nida-Rümelin
doaj  

Using drama to introduce ethics to technology students and practitioners [PDF]

open access: yes, 2009
In this poster we describe the use of Joe Penhall's play 'Landscape with Weapon' as a resource to teach ethics to students and practitioners in technology. 'Landscape with Weapon' is a play in three acts that revolve around issues confronting an engineer
Ferreira, Giselle, Monk, John
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Proceedings of the Conference on Globalization and Its Discontents [PDF]

open access: yes
Increasing globalization and free trade agreements have generated a number of controversies. One significant issue is the potential conflict between free trade and ethical standards.
Joshua Frank
core  

Managing the Ethical Dimensions of Brain-Computer Interfaces in eHealth: An SDLC-based Approach [PDF]

open access: yes, 2016
A growing range of brain-computer interface (BCI) technologies is being employed for purposes of therapy and human augmentation. While much thought has been given to the ethical implications of such technologies at the ‘macro’ level of social policy and ‘
Gladden, Matthew E.
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The Ethical Implications of Personal Health Monitoring [PDF]

open access: yes, 2013
Personal Health Monitoring (PHM) uses electronic devices which monitor and record health-related data outside a hospital, usually within the home. This paper examines the ethical issues raised by PHM.
Mittelstadt, Brent
core   +1 more source

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