Results 91 to 100 of about 3,143,648 (297)

Ethical Foreground and Background in Adult Educator Work

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Ethical Questions Linked to Rare Diseases and Orphan Drugs – A Systematic Review

open access: yesRisk Management and Healthcare Policy, 2020
Jaroslav Kacetl,1 Petra Marešová,2 Raihan Maskuriy,3,4 Ali Selamat5,6 1Department of Linguistics, Faculty of Informatics and Management, University of Hradec Kralove, Hradec Kralove, Czech Republic; 2Department of Economics, Faculty of ...
Kacetl J   +3 more
doaj  

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Ethical principles in health care research [PDF]

open access: yes, 2013
Chapter topics • The history of the evolving recognition of the need to regulate research involving human subjects • Consideration of some key ethical principles relevant to the research process • Applying ethical understanding in the practice ...
Scott, Anne
core   +1 more source

Some Ethical Issues in Research Involving Human Subjects

open access: yes, 1978
First part of an appendix to accompany a report describing the conclusions of the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research regarding ethics in research: "This Appendix contains (in two volumes) the ...
United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research.
core  

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

The ethical tendency typology

open access: yes, 2019
In this chapter, the authors present and describe a typology of how ethics and morals appear in educational practice. The ‘ethical tendency typology’ distinguishes three different kinds of situations: personal moral reactions, norms for correct behaviour
Öhman, Johan,   +3 more
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Ethical Standards Prescribed in The Qur'an

open access: yesRabbanica: Journal of Revealed Knowledge
This research is to understand the ethical tenets elucidated in the Quran and their impact on the formation of a virtuous society, starting with the nurturing of individuals who possess high moral standards.
Zamakhsyari bin Hasballah Thaib
doaj  

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