Results 31 to 40 of about 362,259 (303)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi   +6 more
wiley   +1 more source

The moral commentary of the Holy Qur'an emphasizes its foundations [PDF]

open access: yesتحقیقات علوم قرآن و حدیث, 2018
Ethical interpretation is one of the distinctive features of Quranic commentary, and one of the most important components of this kind of interpretation is its epistemological principles.
Mohammad Reza Shahroodi, Masoumeh Agahi
doaj   +1 more source

Embedding Ethical Principles into AI Predictive Tools for Migration Management in Humanitarian Action

open access: yesSocial Sciences, 2023
AI predictive tools for migration management in the humanitarian field can significantly aid humanitarian actors in augmenting their decision-making capabilities and improving the lives and well-being of migrants.
Andrea Guillén, Emma Teodoro
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Review and Formulation of Ethical Guidelines for the Development and Deployment of Artificial Intelligence Systems [PDF]

open access: yesIranian Journal of Information Processing & Management
The ethics of artificial intelligence is a relatively emerging field within the scope of applied ethics, which is influenced by the transformations driven by the development and deployment of AI systems and examines the ethical and social implications ...
Alireza Seghatoleslami
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Ethical Considerations in the Main Practices of the Iranian Legal Medicine Organization: A Qualitative Study

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2022
Background: Effective and acceptable practice in Legal Medicine (LM) requires special attention to ethical and professional behaviors. In LM, the importance of practitioners’ compliance with ethical standards is higher.
Mohammadnader Sharifi   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Advertisement without Ethical Principles?

open access: yesContemporary Economics, 2007
The article replies to the question, whether the advertisement can exist without ethical principles or ethics should be the basis of the advertisement. One can say that the ethical opinion of the advertisement does not depend on content and the form of ...
Wojciech Słomski
doaj  

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