Results 131 to 140 of about 2,906,189 (349)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility. [PDF]

open access: yesHastings Cent Rep, 2023
Meyer MN   +18 more
europepmc   +1 more source

Ethical Considerations in the Use of Artificial Intelligence and Machine Learning in Health Care: A Comprehensive Review

open access: yesCureus
Artificial intelligence (AI) and machine learning (ML) technologies are revolutionizing health care by offering unprecedented opportunities to enhance patient care, optimize clinical workflows, and advance medical research. However, the integration of AI
Mitul Harishbhai Tilala   +6 more
semanticscholar   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Support of international organizations for a flexible development of corporate social responsibility in European countries [PDF]

open access: yes, 2007
Current appreciation of corporate social responsibility. Fundamental theoretical principles of social responsible enterprise. Basic problem of support for social responsible enterprise - moral scepticism in business area.
Dubcová, Gabriela
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu   +5 more
wiley   +1 more source

The ethical responsibility to continue investigational treatments of research participants in situation of armed conflicts, economic sanctions or natural catastrophes. [PDF]

open access: yesFront Med (Lausanne), 2022
Kerpel-Fronius S   +8 more
europepmc   +1 more source

Corporate social responsibility and banks [PDF]

open access: yes, 2009
Article discussing ethical issues and matters of social responsibility surrounding turmoil in the capital markets, bank failures and government intervention. Article by Charles Chatterjee (Global Policy Institute, London Metropolitan University) and Anna
Chatterjee, Charles, Lefcovitch, Anna
core  

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