Results 11 to 20 of about 1,311,767 (216)

Challenges of Investigator-initiated Clinical Trials to Support 
the New Drug Development

Chinese Journal of Lung Cancer, 2022
A large number of investigator-initiated clinical trials (IIT) were conducted in China, some of them should play an important supporting role in new drug development.
Hua BAI, Shuyang ZHANG
doaj   +1 more source

The ethical responsibility to continue investigational treatments of research participants in situation of armed conflicts, economic sanctions or natural catastrophes

Frontiers in Medicine, 2022
This paper discusses the effects of armed conflict, economic sanctions, and natural catastrophes on ongoing clinical trials. We suggest that• stopping the accrual of new patients in clinical trials under such extreme conditions is acceptable.• research ...
Sandor Kerpel-Fronius, Chieko Kurihara, Francis P. Crawley, Varvara Baroutsou, Sander Becker, Brigitte Franke-Bray, Kotone Matsuyama, Shehla Naseem, Johanna Schenk   +8 more
doaj   +1 more source

Increased Incidence in False Positive Diagnosis of Gestational Diabetes Mellitus with 75gm Oral Glucose Tolerance Test: A Clinical Study in Chinese Women

Journal of Nepal Health Research Council, 2019
Background: Currently, most of the countries across the globe follow the International Association of the Diabetes and Pregnancy Study Groups criteria in the diagnosis of gestational diabetes mellitus, which is based on the analysis of Hyperglycemia and
Kamana K.C., Hua Zhang, Anju Vaidya
doaj   +1 more source

Construction of ethical cooperative review mode based on medical union

Zhongguo linchuang yanjiu, 2023
With the rapid development of biomedical science and technology in China, the number of clinical research projects is increasing rapidly, which is accompanied by ethical challenges.
ZHOU Ren, CAI Mingmin, XIE Bo, XU Min, WANG Huiping   +4 more
doaj   +1 more source

Is mandatory research ethics reviewing ethical? [PDF]

Journal of Medical Ethics, 2012
Review boards responsible for vetting the ethical conduct of research have been criticised for their costliness, unreliability and inappropriate standards when evaluating some non-medical research, but the basic value of mandatory ethical review has not been questioned.
Dyck, Murray, Allen, Gary
openaire   +3 more sources

Ethics review in research [PDF]

BMJ, 2004
EDITOR—Hearnshaw and Glasziou and Chalmers highlight the inconsistencies and arbitrary decision making of UK research ethics committees and show that this may delay and suppress clinical research in the United Kingdom.1 2 I recently submitted a study that required six months, countless emails, and submission of 1443 sheets of A4 paper to gain approval …
openaire   +6 more sources

An empirical study on the ethical issues caused by the experiment of rhesus monkey carrying human brain gene [PDF]

Jichu yixue yu linchuang, 2023
Objective In 2019, A Chinese medical research team constructed a transgenic rhesus monkey model of human MCPH1, which is necessary to understand the cognition and behavior tendency of researchers on this new type of ethical issues.
GUI Yixin, DU Yingjie, ZHANG Xinqing
doaj   +1 more source

Refining Housing, Husbandry and Care for Animals Used in Studies Involving Biotelemetry

Animals, 2014
Biotelemetry can contribute towards reducing animal numbers and suffering in disciplines including physiology, pharmacology and behavioural research.
Penny Hawkins
doaj   +1 more source

The readiness of the Asian research ethics committees in responding to the COVID-19 pandemic: A multi-country survey [version 1; peer review: 2 approved]

F1000Research
Background COVID-19 is a highly challenging infectious disease. Research ethics committees (RECs) have challenges reviewing research on this new pandemic disease under a tight timeline and public pressure.
Asyraf Syahmi Mohd Noor, Kwanchanok Yimtae, Namita Ghimire, Chandanie Wanigatunge, Pradip Gyanwali, Subhanshi Sharma, Harnawan Rizki, Prakash Ghimire, Septi Dewi Rachmawati, Monalisa Waworundeng, Paresh Koli, Lisa Amir, Yashashri Shetty, Sudha Ramalingam, Phanthipha Wongwai, Edlyn B. Jimenez, Cristina E. Torres, Arthur M. Navarro, Juntra Karbwang   +18 more
doaj   +1 more source

The Development and Implementation of a Quality Improvement Review Committee (QIRC): An Ethical and Pragmatic Imperative

Canadian Journal of Bioethics
Background: In complex academic healthcare systems, quality improvement (QI) projects designed to improve care and enhance learning proliferate, yet there is considerable variation with respect to how, or even whether, these projects receive ethical ...
Sarah E. McMillan, Sarah Tosoni, Kerry-Ann Smith, Betty Chau, Paul Oh, Catriona Steele, Lucas B. Chartier, Ann Heesters   +7 more
doaj   +1 more source