Results 81 to 90 of about 1,165,701 (302)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Motivation as Moderating Variable on the Effect of Moral Reasoning and Ethical Sensitivity Toward the Ethical Behavior of Accounting Students

JABE (Journal of Accounting and Business Education), 2019
This research aims to prove the effect of moral reasoning andethical sensitivity on accounting students’ ethical behavior on the basis of motivation as moderating variables.
Sigit Hermawan, Lilin Nur Indah Sari
doaj   +1 more source

Cultural Dimensions, Ethical Sensitivity, and Corporate Governance [PDF]

, 2012
The economic globalization process has integrated different competitive markets and pushes firms in different countries to improve their managerial and operational efficiencies.
Chan, AWH, Cheung, HY
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Ontological imagination: transcending methodological solipsism and the promise of interdisciplinary studies [PDF]

, 2013
This text is a presentation of the notion of ontological imagination. It constitutes an attempt to merge two traditions: critical sociology and science and technology studies - STS.
Nowak, Andrzej W.
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Developing a Moral Sensitivity Measure for Career Guidance and Counselling

Journal for Perspectives of Economic Political and Social Integration, 2020
Moral sensitivity, the ability to recognize ethical issues when they arise in practice, is a key premise for career practitioners’ professional conduct of Career Guidance Counselling (CGC).
Johannes Katsarov, Anouk J. Albien, Lea Ferrari   +2 more
doaj   +1 more source

Pengaruh Orientasi Etika, Komitmen Profesional, Komitmen Organisasi, dan Sensitivitas Etis terhadap Internal Whistleblowing (Studi Empiris pada Skpd Kota Pekanbaru) [PDF]

, 2017
This research aimed to know the influence of the Idealism Ethical Orientation, Relativism Ethical Orientation, professional commitment, Organizational Commitment and Ethical Sensitivity to the Internal Whistleblowing.
Hardi, H. (Hardi), Janitra, W. A. (Wimpi), Wiguna, M. (Meilda)   +2 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

SENSITIVITAS ETIS DAN PERTIMBANGAN MORAL MAHASISWA AKUNTANSI TERHADAP DILEMA BISNIS

Jurnal Akuntansi, 2019
and perceived societal pressure) to the ethical sensitivity and moral judgments of accounting students and to prove the influence of the dimension of moral intensity to the moral judgments through ethical sensitivity.
Kiki Apriyana, Lisa Martiah Nila Puspita
doaj   +1 more source