Results 141 to 150 of about 38,041 (341)
Research cloning gets green light from Japanese ethicists [PDF]
David Cyranoski
openalex +1 more source
Ethics Brewed in an African Pot [PDF]
Doing ethics in African Christianity raises the challenge of over-generalization in the midst of diversity and variety. This essay surveys the wide ethical landscape of Africa, explores key ethical issues on the continent within the context of the world ...
Orobator, Agbonkhianmeghe E.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
What’s Unethical About Interprofessional Collaboration?
In this commentary, the beneficial value of the relational aspects of interprofessional collaboration is emphasized to demonstrate that conflict of interests arising in self-referrals are more complex than presented in classic cases of conflicts of ...
Lévesque, Lise
doaj
Why Aristotle Isn’t a Virtue Ethicist. Living Well and Virtuously in Aristotelian and Contemporary Aretaic Ethics [PDF]
Deniz A. van den Woldenberg
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Comment on: What to do during inflight medical emergencies? Practice pointers from a medical ethicist and an aviation medicine specialist [PDF]
Zohar Lederman
openalex +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Nudge Me If You Can! Why Order Ethicists Should Embrace the Nudge Approach [PDF]
Nikil Mukerji, Adriano Mannino
openalex +1 more source

