Results 131 to 140 of about 3,042,993 (293)

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Deep Ecology and End-of-Life Care

, 2009
Physicians and nurses caring for terminally ill patients are expected to center their moral concerns almost exclusively on the needs and welfare of the dying patient and the patients family.
Carrick, Paul
core  

Quicksands of Compromise [PDF]

, 1972
In his address to the November, 1971 Meeting of the National Federation of Catholic Physicians\u27 Guilds in New Orleans Dr. Brennan defended the acceptance of the revised code of medical ethics.
Brennan, John J.
core   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Le médecin-écrivain, l’éthique et l’imaginaire [PDF]

Les Ateliers de l’Ethique, 2010
There are many physician writers worldwide, but the ties that bind a health professional's expe- rience to his/her fiction writing have been studied more extensively in the English-speaking Literary and Medical world than in its French language ...
Marc Zaffran
doaj  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Journal of Medical Ethics and History of Medicine Contributors

Journal of Medical Ethics and History of Medicine, 2021
Journal of Medical Ethics & History of Medicine
doaj  

A Comparative Analysis on Ethical Benchmarking in Large Language Models [PDF]

arXiv
This work contributes to the field of Machine Ethics (ME) benchmarking, which develops tests to assess whether intelligent systems accurately represent human values and act accordingly. We identify three major issues with current ME benchmarks: limited ecological validity due to unrealistic ethical dilemmas, unstructured question generation without ...
arxiv  

MEDICAL ETHICS EDUCATION IN TURKEY; STATE OF PLAY and CHALLENGES [PDF]

, 2016
Medical ethics can be traced back to Hippocratic oat in antiquity. Last decade witnessed improvements in science and technology which attracted attention to the ethical impacts of the innovations in medicine.
Ekmekçi, Perihan Elif
core   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source