Results 201 to 210 of about 3,141,195 (309)
Correction: Mertz et al. Interdisciplinary Animal Research Ethics-Challenges, Opportunities, and Perspectives. <i>Animals</i> 2024, <i>14</i>, 2896. [PDF]
Mertz M+13 more
europepmc +1 more source
Stage‐Dependent Inhibitory Connectivity in Striatal‐Motor Circuit in Huntington's Disease
ABSTRACT Background Elucidating dysfunctional connectivity patterns among key brain regions in Huntington's disease (HD) underlying progression may have implications for developing treatment and therapeutic evaluation. Objective Explore the relationship between abnormal spontaneous resting‐state activity and atrophy in HD‐specific brain regions and ...
Yinghua Jing+4 more
wiley +1 more source
Construction and validation of a predictive model for the acceptance of kidney xenotransplantation among patients awaiting kidney transplantation: a cross-sectional study from China. [PDF]
Yang S+5 more
europepmc +1 more source
BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach+11 more
wiley +1 more source
Strengthening ethical oversight in genomics and biobanking: a retrospective analysis of research practices in Zimbabwe. [PDF]
Kuguyo O+7 more
europepmc +1 more source
ABSTRACT This case described a 25‐year‐old pregnant woman with refractory multifocal epilepsy, diagnosed in 2020 and treated with bilateral thalamic deep brain stimulation (DBS) targeting the centromedian and pulvinar nuclei. Prior to DBS, she experienced daily focal seizures, often progressing to generalized tonic–clonic seizures despite optimal ...
Shalin Shah+4 more
wiley +1 more source
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos+11 more
wiley +1 more source
Distinctive characteristics of female nurse leaders: a qualitative study. [PDF]
Khodamorovati M+4 more
europepmc +1 more source