Results 31 to 40 of about 3,255,608 (287)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Zhongguo gonggong weisheng, 2023 With the rapid and in-depth development of medical practice and medical research, medical ethics issues are receiving more and more attention; at the same time, population-related health surveys are also facing more and more medical ethics issues. How to
Hui-nan HAN, Xiao-yu WANG, Li-ping HAN
doaj +1 more source
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
American Journal of Islam and Society, 1996 It was indeed an auspicious occasion when experts in different academic fields came together to discuss questions confronting Muslim society based on recent medical advancements.
Khurshid Ahmad Nadeem
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Patient Suffering and the Anointing of the Sick [PDF]
, 1992 Anthologized in On Moral Medicine: Theological Perspectives in Medical Ethics, 2nd edition. Edited by Stephen E. Lammers and Allen Verhey. Grand Rapids: Eerdmans, 1998, 356-364. And in On Moral Medicine: Theological Perspectives in Medical Ethics, 3rd
Lysaught, M. Therese
core +1 more source
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
The relationship between medical law and good medical ethics [PDF]
, 2014 In the UK, medical ethics and law are often thought of and taught together, but while ‘good medical ethics’ is often reflected in law–the need to obtain a patient's adequately informed consent, for example—this is not necessarily the case.
Jackson, Emily
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