Results 71 to 80 of about 3,141,195 (309)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Ethical approval in developing countries is not optional [PDF]

open access: yes, 2012
When conducting health and medical research it is not only important to do the research ethically, but also to apply for prior ethical approval from the relevant authorities.
Simkhada, Padam, van Teijlingen, Edwin
core   +1 more source

Comparison of the Medical Ethics Approaches according to Professional Experience and the Source of Medical Ethics Training: A Survey Study

open access: yesErciyes Medical Journal, 2020
Objective: This study aimed to compare the perspective on, the standard of knowledge and perceptions of medical ethics in the sixth-grade medical faculty students of a university hospital and the residents and academics working in the same hospital ...
Türev Demirtaş
doaj   +1 more source

MEDICAL ETHICS AND MEDICAL JOURNALS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1900
To most of us the average paper concerning our intraprofessional relations is somewhat tiresome. In many quarters the dignity of medical ethics has been most loudly preached by those lacking experience in its practice. It is little to be wondered at, therefore, that the subject is not a popular medical society topic.
openaire   +2 more sources

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Clinical ethics: medical tourism in children. [PDF]

open access: yesArch Dis Child, 2021
Birchley G   +3 more
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Students’ medical ethics rounds: a combinatorial program for medical ethics education

open access: yesJournal of Medical Ethics and History of Medicine, 2016
It has long been a common goal for both medical educators and ethicists to develop effective methods or programs for medical ethics education.
Maani Beigy   +6 more
doaj  

Discussão Ética sobre o Prontuário Eletrônico do Paciente

open access: yesRevista Brasileira de Educação Médica
RESUMO O prontuário do paciente constitui uma ferramenta fundamental para a prestação do cuidado em saúde, podendo ser definido como um registro padronizado e organizado de toda a informação referente à saúde de um indivíduo, desde o nascimento até a ...
Maria José Guedes Gondim Almeida   +3 more
doaj   +1 more source

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