Results 41 to 50 of about 1,901,964 (344)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Conflict of roles, a conflict of ideas? The unsettled relations between care team staff and independent mental health advocates. [PDF]

, 2014
Drawing on a national study of Independent Mental Health Advocacy we explore the social relations of independent advocacy. The study was commissioned by the Department of Health (England) and involved a case study design covering eight different ...
Ahern, Bateman, Bernal, Bindman, Black, Boyle, Brandon, Breeding, Campbell, Campbell, Care Quality Commission, Care Quality Commission, Cleary, Coffey, Dalrymple, Davis, Fernando, Fourie, Gamble, Gates, Gates, Gostin, Hanks, Happell, Harrison & Davis, Hart, Henderson, Hewitt, Holmes, Ingleby, Jackson, Jenny, Jones, Juggessur, Kapasi, MacDonald, Mallik, Mallik, Martin, Miller, MIND, Nelson, Newbigging, Post, Pullen, Randall, Robinson, Rose, Rosenman, Royal College of Psychiatrists, Sang, Snowball, Thacker, The Mental Health Foundation, Tyrer, Usher, Vaartio, Walsh, Willard, Williams, Wolfensburger, World Health Organization, Zinkler, Zomorodi   +63 more
core   +1 more source

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block, Shane Poole, Leah McIntyre, Nikki Sisodia, Chelyn Park, Gabby Joseph, Michelle E. Van Kuiken, Anne M. Suskind, Riley Bove   +8 more
wiley   +1 more source

THE TEACHING OF ETHICS AND BIOETHICS IN THE NURSES’ FORMATIONPROCESS REGARDING THE NATIONAL CURRICULUM GUIDELINES

Cogitare Enfermagem, 2009
Theoretical reflection of the teaching of ethics/bioethics in undergraduate nursing programs in Brazil, by theethical point of view. The objective is to reflect about the teaching of ethics/bioethics and the National Curricular Guidelinesin Nursing.
Janieiry Lima de Araújo, Maria Salete Bessa Jorge, Consuelo Helena Aires de Freitas, Thereza Maria Magalhães Moreira   +3 more
doaj   +1 more source

Real‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...
Sarmad Al‐Araji, Marcello Moccia, Alessia Bianchi, Charmaine Yam, Weaam Hamed, Suraya Mohamud, Alan J. Thompson, Frederik Barkhof, Ahmed T. Toosy, Olga Ciccarelli   +9 more
wiley   +1 more source

Consulted ethical problems of clinical nursing practice: perspective of faculty members in Japan

BMC Nursing, 2017
Background There are several studies that have targeted student nurses, but few have clarified the details pertaining to the specific ethical problems in clinical practice with the viewpoint of the nursing faculty.
Mari Tsuruwaka
doaj   +1 more source

Ethics as Applied to Nursing [PDF]

The American Journal of Nursing, 1916
n ...
openaire   +2 more sources

Cameras on beds: The ethics of surveillance in nursing home rooms

AJOB Empirical Bioethics, 2019
Surveillance cameras are increasingly being deployed in nursing homes and assisted living facilities, with insufficient attention to what is ethically fraught about this way of assuaging concerns about abuse and other personnel challenges.
C. Berridge, J. Halpern, K. Levy
semanticscholar   +1 more source

Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age‐ and BMI‐Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Maximilian Einsiedler, Aleksandra Maleska Maceski, Sofia Sandgren, Johanna Oechtering, Sabine Schaedelin, Lisa Hofer, Amar Zadic, Juan Francisco Vilchez Gomez, Lester Melie‐Garcia, Alessandro Cagol, Riccardo Galbusera, Sebastian Finkener, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Amandine Mathias, Renaud Du Pasquier, Robert Hoepner, Andrew Chan, Giulio Disanto, Chiara Zecca, Marcus D’Souza, Lars G. Hemkens, Tobias Derfuss, Özgür Yaldizli, Patrick Roth, Claudio Gobbi, David Brassat, Björn Tackenberg, Henrik Zetterberg, Tjalf Ziemssen, Heinz Wiendl, Klaus Berger, Marco Hermesdorf, Fredrik Piehl, Ludwig Kappos, Cristina Granziera, Ahmed Abdelhak, David Leppert, Eline A. J. Willemse, Pascal Benkert, Jens Kuhle, Swiss Multiple Sclerosis Cohort Study (SMSC)   +43 more
wiley   +1 more source

Validation of the Santa Clara Ethics Scale (SCES) in Nursing Students: The Role of Ethics as a Protector of Student Compassion

Nursing Reports
Background: Ethics is one of the essential concepts associated with professional nursing practice, and can play a part in the development of compassion. Although a number of instruments have been developed for the measurement of ethics, most are context ...
Gabriel Vidal-Blanco, Javier Sánchez-Ruiz, Laura Galiana, Antonia Pades, Noemí Sansó   +4 more
doaj   +1 more source