Results 111 to 120 of about 3,912,951 (289)
CV Joints: A case study for use in teaching in Engineering Ethics [PDF]
, 2010 This is an Engineering Ethics case study from the IDEA CETL. The scenario examines issues around the intellectual property of an idea possibly inspired by working at a company.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds +2 more
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
St Andrews Encyclopaedia of TheologyIt may be argued that religion, in its most elemental form, comprises two dimensions: (1) a worldview or weltanschauung, that is to say, a conception about the nature and structure of reality (i.e.
Atif Khalil
doaj
A scoping review of ethical decisions and decision tools for experimental animal protocols
BMC Medical EthicsBackground Scientific research projects involving animals are required to undergo ethical evaluation, generally known as harm-benefit analysis (HBA), to ensure that they address important ethical concerns related to animal welfare and the scientific ...
David Mawufemor Azilagbetor +5 more
doaj +1 more source
Transmission Towers: A case study for use in teaching in Engineering Ethics [PDF]
, 2010 This is an Engineering Ethics case study from the IDEA CETL. It examines the moral issues surrounding a disagreement with a boss at work concerning the safety of a transmission tower. It considers safety and risk and whistleblowing.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds +1 more
core
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Journal of Medical Ethics and History of Medicine Contributors
Journal of Medical Ethics and History of Medicine, 2021 Journal of Medical Ethics & History of Medicine
doaj
French Engineers: A case study for use in teaching in Engineering Ethics [PDF]
, 2010 This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the problem of what to do when encountering unacceptable behaviour (drinking during work hours) while working abroad. It raises issues such as moral relativism; safety and
Inter-Disciplinary Ethics Applied Cetl, University of Leeds +1 more
core
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source