Results 151 to 160 of about 3,110,108 (316)

Equipoise and the ethics of randomization.

, 1995
Richard Lilford, J Jackson
openalex   +1 more source

The Ethics of Wasaṭīyah and the Pursuit of Gender Equality

, 2015
Etin Anwar
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Correction: PM2.5 risk perception and associated with sociodemographic factors in urban Thailand. [PDF]

Sci Rep
Luangwilai T, Ong-Artborirak P, Manomaipiboon B, Ruamtawee W, Kunno J.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Do Funders, Regulators, and Ethics Bodies Support Informative Trials? A Content Analysis of Global Guidance Documents. [PDF]

J Eval Clin Pract
Prowse SR, Brazzelli M, Bruhn H, Treweek S.   +3 more
europepmc   +1 more source

“To Me, It Was Significant”: The Ethics of Returning Variants of Uncertain Significance from Clinical Exome Sequencing

, 2018
Kristin Clift, Colin Halverson, Jennifer B. McCormick   +2 more
openalex   +1 more source

“Cloud’s red, earth feeling, sky that thinks”: John Banville’s Aesth/ethics / “Nuvem vermelha, terra sentindo, céu que pensa”: Est/ética de John Banville

, 2020
Joakim Wrethed
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Ethical awareness and issues in gastrointestinal endoscopy practice: A survey study. [PDF]

World J Gastroenterol
Qin Y, Shi MY.
europepmc   +1 more source