Results 181 to 190 of about 5,958,087 (357)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Retraction: Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

5. Development and Ethics

, 2022
Kristien Hens
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

The Impact of Science on Fake Meat: Balancing Cost and Ethics

, 2023
YouAI Han
openalex   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Correction: A collaborative approach of finite element method and machine learning algorithms for biomechanical analysis of implants used in tibial shaft fractures. [PDF]

BMC Musculoskelet Disord
Mutu HB.
europepmc   +1 more source

Ghostly Ethics [PDF]

Medical Anthropology, 2018
openaire   +3 more sources

Ethical Problems, Ethical Interrogations and Ethical Responses

African Journal of Stability and Development (AJSD)
By showing how philosophers probe into and respond to ethical issues, this paper discusses the nature of ethical problems. It examines the contentions between traditional and non-traditional ethical perspectives by evaluating the ideas of certain philosophers that cast aspersion on traditional views of ethics.
openaire   +1 more source

Symposium on Revenue Transparency, Resource Development, and the Challenge of Corruption [PDF]

Revenue transparency and corruption in the mining industry have long been topics of national and international conversation. Mining plays an important role in the Canadian economy, contributing billions to Canada’s GDP.
Canadian Business Ethics Research Network (CBERN)
core