Results 41 to 50 of about 2,457,030 (220)

Multi-disciplinary research ethics review: is it feasible? [PDF]

open access: yes, 2006
This paper reviews the currently rapid changes in research ethics governance affecting many kinds of social research. Arguments for and against single‐discipline and multidisciplinary research ethics committees will be considered, with examples of how ...
Alderson, Priscilla, Morrow, Virginia
core   +3 more sources

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption

open access: yesMolecular Oncology, EarlyView.
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso   +12 more
wiley   +1 more source

Making ethical decisions for the immersive web [PDF]

open access: yesarXiv, 2019
Mixed reality (MR) ethics occupies a space that intersects with web ethics, emerging tech ethics, healthcare ethics and product ethics (among others). This paper focuses on how we can build an immersive web that encourages ethical development and usage.
arxiv  

How Much Should We Expect of Ourselves? with Marcus Hedahl and Kyle Fruh [PDF]

open access: yes, 2023
Overview & Shownotes We’re exploring the philosophical problem known as “demandingness” with Kyle Fruh and Marcus Hedahl. We discuss how much we should expect of ourselves when it comes to fighting climate change, and how to meet moral demands without ...
Fruh, Kyle   +2 more
core   +1 more source

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern   +8 more
wiley   +1 more source

Disciplinary Action Ethics Violations [PDF]

open access: yes, 2020
Disciplinary Actions for Ethics Violations All State employees are mandated to follow the rules included in such statutes as the Uniform Ethics Code and the New Jersey Conflicts of Interest Law.
Ethics Office
core   +1 more source

Thinking While Walking with Martin Bunzl [PDF]

open access: yes, 2021
Overview & Shownotes The philosopher Martin Bunzl and he loves living near the Pacific Crest Trail because it allow him to explore nature. The famous foot path also inspired him to embark on a new project of thinking while walking.
Bunzl, Martin, Wisehart, Christiane
core  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Introduction: The Fogarty International Research Ethics Education and Curriculum Development Program in Historical Context [PDF]

open access: yes, 2013
In response to the increasing need for research ethics expertise in low and middle income countries (LMICs), the NIH's Fogarty International Research Ethics Education and Curriculum Development Program has provided grants for the development of training ...
Grady, Christine   +3 more
core   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

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