Results 81 to 90 of about 3,912,951 (289)

An Ancient Dilemma: A case study for use in teaching in Engineering Ethics [PDF]

open access: yes, 2010
This is an Engineering Ethics case study from the IDEA CETL. The scenario examines the case of a conflict between completing a project on time and within budget and respecting the demands of heritage.
Inter-Disciplinary Ethics Applied Cetl, University of Leeds
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Cataloging Code of Ethics

open access: yes, 2021
The document was drafted by the Cataloging Ethics Steering Committee (CESC) in consultation with six Working Groups and members of the international cataloging community of practice.
Cataloging Ethics Steering Committee
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Relational Attributes Associated with Treatment Adherence: A Scoping Review

open access: yesPatient Preference and Adherence
Yi Jiao Angelina Tian,1 Emma Herger,1 Aoife Milford,1 Stephen Milford1,21Institute for Biomedical Ethics, University of Basel, Basel, Switzerland; 2Faculty of Theology, North-West University, Potchefstroom, South AfricaCorrespondence: Yi Jiao Angelina ...
Tian YJA, Herger E, Milford A, Milford S
doaj  

Uncovering the social impact of digital steganalysis tools applied to cybercrime investigations: a European Union perspective

open access: yesCrime Science
Background European Union (EU) research on cybersecurity is actively developing more efficient digital steganalysis techniques aimed at uncovering hidden online illegal content in apparently legitimate multimedia files.
Alejandro Nicolás-Sánchez   +1 more
doaj   +1 more source

Analyzing the European institutional response to ethical and regulatory challenges of artificial intelligence in addressing discriminatory bias

open access: yesFrontiers in Artificial Intelligence
The European Union and some of its institutions have taken significant steps to address the challenges posed by the development and use of Artificial Intelligence (AI) in various contexts.
Pablo Cerezo-Martínez   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Sync fast and solve things—best practices for responsible digital health

open access: yesnpj Digital Medicine
Digital health innovation is expected to transform healthcare, but it also generates ethical and societal concerns, such as privacy risks, and biases that can compound existing health inequalities.
Constantin Landers   +2 more
doaj   +1 more source

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