Results 121 to 130 of about 505,131 (352)

Getting Beyond Form Filling: The Role of Institutional Governance in Human Research Ethics [PDF]

, 2018
It has become almost a truism to describe the interaction between research ethics committees and researchers as being marred by distrust and conflict.
Allen, Gary
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Caracterização de protocolos de pesquisa: um estudo na Paraíba, Brasil

Revista Bioética
Resumo O artigo apresenta a caracterização da totalidade dos protocolos de pesquisa apreciados pelo Comitê de Ética em Pesquisa do Instituto Federal da Paraíba (CEP/IFPB), desde sua fundação, em 2008, até 2014. Trata-se de estudo descritivo e documental,
Genésio José da Silva, Maria Luiza da Costa Santos   +1 more
doaj   +1 more source

Advisory Opinions Issued by Ethics Committee [PDF]

, 1987

openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Conhecimento e envolvimento de graduandos em fisioterapia acerca dos preceitos éticos da experimentação animal

Revista Bioética
O artigo analisa em amostra de universitários do curso de fisioterapia indicadores éticos ao uso de animais na pesquisa e no ensino e o nível de conhecimento e interesse dos alunos sobre o tema ética animal.
Igor Fagioli Bordello Masson, Cristiano Schiavinato Baldan, Vanessa Reimberg Ramalho, Ivaldo Esteves Junior, Daniela Fagioli Masson, Beatriz de Oliveira Peixoto, Cassio Marcos Vilicev, Thiago Saikali Farcic   +7 more
doaj  

Observational study of 353 applications to London multicentre research ethics committee 1997-2000 [PDF]

, 2002
Malcolm Boyce
openalex   +1 more source

Committees: Research Ethics Committees

, 2014
Radi se o članku koji daje pregled rada i funkcija istraživačkih etičkih povjerenstava.
openaire   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Ethical issues in clinical research

Indian Journal of Plastic Surgery, 2007
Thatte Urmila
doaj   +1 more source