Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Reproductive Technologies, Care Crisis and Inter-generational Relations in North India: Towards a Local Ethics of Care. [PDF]
Asian Bioeth Rev, 2021 Mishra P.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
A 10-Step Method for Fair Priority-Setting Processes: A Qualitative Case Study from Zanzibar
Health Systems & ReformHealth systems worldwide face challenges in managing resource scarcity, necessitating systematic and fair approaches to prioritize essential health services.
Omar Mwalim +14 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
COVID-19, ethics of care and feminist crisis management. [PDF]
Gend Work Organ, 2020 Branicki LJ.
europepmc +1 more source
Supreme Court Leaks and Recusals: A Response to Professor Steven Lubet\u27s SCOTUS Ethics in the Wake of NFIB v. Sebelius [PDF]
, 2013 As Professor Steven Lubet notes in his article, Stonewalling, Leaks, and Counter-Leaks: SCOTUS Ethics in the Wake of NFIB v. Sebelius, the ethical conduct of Supreme Court Justices has once again gained national attention. This time, however, the context
Hopkins, Kevin
core +3 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Close Encounters of the First Kind: An Interdisciplinary Ethics of Care Approach Mitigates Moral Injury and Family Division in the Midst of Covid-19. [PDF]
J Pain Symptom Manage, 2022 Berlin A.
europepmc +1 more source
An assessment of the levels of ethical perception among public University student in Malaysia [PDF]
, 2003 Ethics is indeed crucial because we will not survive the 21st century with the 20th century ethics. With the onset of globalization, many hands guide the controls and many decisions move those hands whose core values play an instrumental role in creating
Low, Hock Heng +2 more
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