Results 21 to 30 of about 1,599,330 (263)

Attitudes and experiences of European clinical geneticists towards direct-to-consumer genetic testing: a qualitative interview study

New Genetics and Society, 2019
Direct-to-consumer (DTC) genetic tests (GT) enable consumers to access a wide range of GT, without involving a healthcare professional, promoting an increasing disassociation of genetics from the clinical context.
Louiza Kalokairinou, Pascal Borry, Heidi C. Howard   +2 more
doaj   +1 more source

Contextualization of cost-effectiveness evidence from literature for 382 health interventions for the Ethiopian essential health services package revision

Cost Effectiveness and Resource Allocation, 2021
Background Cost-effectiveness of interventions was a criterion decided to guide priority setting in the latest revision of Ethiopia’s essential health services package (EHSP) in 2019.
Alemayehu Hailu, Getachew Teshome Eregata, Amanuel Yigezu, Melanie Y. Bertram, Kjell Arne Johansson, Ole F. Norheim   +5 more
doaj   +1 more source

The Influence of Trauma on End-of-Life Decision-Making

Canadian Journal of Bioethics
This case study illustrates how principles and approaches from trauma-informed care can be used in a setting where a family is requesting the medical team not to share bad news out of fear of re-traumatization.
Maya Nortjé, Maureen Pontarelli, Ian Doherty, Karen Terrell, Carla Robles, Nico Nortjé   +5 more
doaj   +1 more source

Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review [version 2; peer review: 1 approved, 2 approved with reservations]

Open Research Europe
Background Direct-to-consumer genetic testing (DTC-GT) which provides genetic information directly to the public, has become widely available at a moderate cost.
Maria Siermann, Eva Van Steijvoort, Alexandra Stanczak, Pascal Borry, Kenji Demesure, Kaatje Goossens   +5 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Ethical and Policy Issues in Human Fetal Tissue Transplants

Cell Transplantation, 1995
A review of human fetal tissue policies over the past 40 years reveals an increasing awareness that the use of this tissue raises unique ethical and policy issues.
Dorothy E. Vawter, Karen G. Gervais
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Cancer and COVID-19: ethical issues concerning the use of telemedicine during the pandemic

BMC Health Services Research, 2022
The lockdown imposed in France during the first wave of the COVID-19 pandemic wreaked havoc with access to healthcare. From March 2020 onwards, the oncologists of Foch Hospital, like many others at hospitals throughout the world, were obliged to adapt to
Lucas Huret, Henri-Corto Stoeklé, Asmahane Benmaziane, Philippe Beuzeboc, Christian Hervé   +4 more
doaj   +1 more source

Polygenic risk scoring of human embryos: a qualitative study of media coverage

BMC Medical Ethics, 2021
Background Current preimplantation genetic testing (PGT) technologies enable embryo genotyping across the whole genome. This has led to the development of polygenic risk scoring of human embryos (PGT-P).
Tiny Pagnaer, Maria Siermann, Pascal Borry, Olga Tšuiko   +3 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source