Results 21 to 30 of about 1,595,917 (265)

Contextualization of cost-effectiveness evidence from literature for 382 health interventions for the Ethiopian essential health services package revision

Cost Effectiveness and Resource Allocation, 2021
Background Cost-effectiveness of interventions was a criterion decided to guide priority setting in the latest revision of Ethiopia’s essential health services package (EHSP) in 2019.
Alemayehu Hailu, Getachew Teshome Eregata, Amanuel Yigezu, Melanie Y. Bertram, Kjell Arne Johansson, Ole F. Norheim   +5 more
doaj   +1 more source

Attitudes and experiences of European clinical geneticists towards direct-to-consumer genetic testing: a qualitative interview study

New Genetics and Society, 2019
Direct-to-consumer (DTC) genetic tests (GT) enable consumers to access a wide range of GT, without involving a healthcare professional, promoting an increasing disassociation of genetics from the clinical context.
Louiza Kalokairinou, Pascal Borry, Heidi C. Howard   +2 more
doaj   +1 more source

Ethical and Policy Issues in Human Fetal Tissue Transplants

Cell Transplantation, 1995
A review of human fetal tissue policies over the past 40 years reveals an increasing awareness that the use of this tissue raises unique ethical and policy issues.
Dorothy E. Vawter, Karen G. Gervais
doaj   +1 more source

Cancer and COVID-19: ethical issues concerning the use of telemedicine during the pandemic

BMC Health Services Research, 2022
The lockdown imposed in France during the first wave of the COVID-19 pandemic wreaked havoc with access to healthcare. From March 2020 onwards, the oncologists of Foch Hospital, like many others at hospitals throughout the world, were obliged to adapt to
Lucas Huret, Henri-Corto Stoeklé, Asmahane Benmaziane, Philippe Beuzeboc, Christian Hervé   +4 more
doaj   +1 more source

Sharing behavior and health care utilization following direct-to-consumer genetic testing: a systematic review [version 2; peer review: 1 approved, 2 approved with reservations]

Open Research Europe
Background Direct-to-consumer genetic testing (DTC-GT) which provides genetic information directly to the public, has become widely available at a moderate cost.
Maria Siermann, Eva Van Steijvoort, Alexandra Stanczak, Pascal Borry, Kenji Demesure, Kaatje Goossens   +5 more
doaj   +1 more source

Polygenic risk scoring of human embryos: a qualitative study of media coverage

BMC Medical Ethics, 2021
Background Current preimplantation genetic testing (PGT) technologies enable embryo genotyping across the whole genome. This has led to the development of polygenic risk scoring of human embryos (PGT-P).
Tiny Pagnaer, Maria Siermann, Pascal Borry, Olga Tšuiko   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Patient experience of communication consistency amongst staff is related to nurse–physician teamwork in hospitals

Nursing Open, 2020
Aim To investigate whether nurse reported teamwork with physicians was associated with patient perceived consistency in staff‐to‐patient communication. Design A cross‐sectional survey design was used, drawing on data collected from two surveys in England.
Mia vonKnorring, Peter Griffiths, Jane Ball, Sara Runesdotter, Rikard Lindqvist   +4 more
doaj   +1 more source

The European Union and Public Health Emergencies: Expert Opinions on the Management of the First Wave of the COVID-19 Pandemic and Suggestions for Future Emergencies

Frontiers in Public Health, 2021
Objective: The first wave of the coronavirus SARS-COV-2 pandemic has revealed a fragmented governance within the European Union (EU) to tackle public health emergencies.
Marie Gontariuk, Thomas Krafft, Cassandra Rehbock, David Townend, Loth Van der Auwermeulen, Eva Pilot   +5 more
doaj   +1 more source