Results 121 to 130 of about 147,555 (214)

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

Journal of Applied Toxicology, Volume 46, Issue 9, Page 2985-2996, September 2026.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara, Brenda Casado, Miguel Betancourt, Adyeni Barajas‐Salinas, Eduardo Casas, Gabriela Hurtado‐Alvarado, Juan José Rodríguez‐Mercado, Alma López, Iván Bahena, Lizbeth Juárez‐Rojas, Leticia González‐Núñez, Fahiel Casillas   +11 more
wiley   +1 more source

Acrylamide‐Induced Developmental and Molecular Toxicity in Drosophila melanogaster: The Role of Vanillic Acid in CncC/Keap1 Modulation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Vanillic acid, a dietary phenolic, dose‐dependently protects Drosophila melanogaster from acrylamide‐induced oxidative damage, DNA strand breaks, and developmental toxicity by modulating CncC/Keap1 redox signaling—establishing vanillic acid as a candidate natural protective agent against a major environmental contaminant.
Fahriye Zemheri‐Navruz, Sinan Ince, Gamze Ataman   +2 more
wiley   +1 more source

Assessment of Genotoxic, Oxidative Stress and Histopathological Effects of Azo Dye Acid Red 119 on Blood and Gill of Freshwater Fish Channa punctata

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Azo dye Acid Red 119 exerts marked DNA damage, oxidative stress, antioxidant enzymatic, and histopathological alterations in the blood and gills of freshwater fish Channa punctata, underscoring the urgent need for stricter effluent regulation and sustainable treatment strategies in textile industries.
Harpal Kaur, Divya Saini, Aditi Khanna, Pooja Chadha   +3 more
wiley   +1 more source

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources

Effects of Lactobacillus Alone and in Combination With Saccharomyces as Alternatives to Antibiotics on Performance and Immunity in Laying Hens

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Supplementation with Lactobacillus plantarum alone or combined with Saccharomyces cerevisiae improved laying performance, egg quality, immune response and caecal microbial balance by increasing beneficial lactic acid bacteria and reducing coliforms, demonstrating probiotics as a safe and sustainable alternative to antibiotic growth promoters in ...
Md. Jahangir Alam, Sonia Tabasum Ahmed, Md. Saiful Islam, Mahfuzul Islam, Md. Mahabbat Ali, Sang‐Suk Lee   +5 more
wiley   +1 more source

Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Survey of Gastrointestinal Parasites of Farmed Pigs in Ghana Gastrointestinal parasites were common in pigs sampled from Kpone Katamanso Municipality, Ghana, with an overall prevalence of 67.6%. Complementary formol–ether concentration, modified McMaster, and modified Ziehl–Neelsen techniques improved parasite detection, while polymerase chain reaction
Antoinette V. Keleve, Sylvia Afriyie Squire, Doreen Dela Owusu‐Ntumy, Dennis Adusei, Linda Ama Owusuaa Amoah   +4 more
wiley   +1 more source

Antibacterial Efficacy of 6‐Gingerol Alone and in Combination With Enrofloxacin Against Multidrug‐Resistant Staphylococcus aureus Isolated From Goats

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Integrated mastitis screening effectively identified MRSA‐associated Staphylococcus aureus in goats, with the Surf Field Mastitis Test proving a reliable rapid diagnostic tool. Combination therapy of enrofloxacin and 6‐gingerol showed superior antibacterial activity, highlighting 6‐gingerol as a promising adjunct to combat antimicrobial‐resistant ...
Maria Khan, Arshad Zahoor, Shabana Naz, Caterina Losacco, Sohail Ahmad, Ibrahim A. Alhidary, Luciana Rossi, Rifat Ullah Khan, Huda A. Alqahtani   +8 more
wiley   +1 more source

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

Aging Cell, Volume 25, Issue 9, September 2026.
Yoda1‐induced Piezo1 activation enhances Piezo1‐Cx43 interaction upon mechanical stimulation, triggering PI3K‐Akt signaling to drive Cx43 phosphorylation and hemichannel opening. These events elevate PGE2 release, suppress SOST expression in senescent osteocytes, and ultimately enhance bone anabolism on the endosteal surface.
Dezhi Zhao, Jiayue Fu, Han Liu, Shuting Liang, Mingming Song, Aining Zhang, Dong‐en Wang, Qianjin Guo, You Zhang, Jiawei Wu, Huiyun Xu   +10 more
wiley   +1 more source

Moderating effects of crocin on some stress oxidative markers in rat brain following demyelination with ethidium bromide. [PDF]

Heliyon, 2019
Fathimoghadam H, Farbod Y, Ghadiri A, Fatemi R.   +3 more
europepmc   +1 more source

Reversible Coordination Modes in Piperazine‐Based Ru(II)‐p‐Cymene Acylthiourea Complexes: Modulating DNA Groove Binding for Selective Antimelanoma Activity

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Piperazine‐based monodentate and S,N‐bidentate Ru(II)‐p‐cymene complexes were synthesized through distinct coordination strategies and evaluated for antimelanoma activity. Among the investigated compounds, the S,N‐bidentate complex 2b exhibited significantly enhanced cytotoxicity (IC50 = 6.1 ± 0.8 ) against melanoma cells, particularly the A375 cell ...
Amir Karim, Xin Wang, Yu‐Ting Chu, Rahimeh Eshaghi Malekshah, En‐De Shu, Najeeb Ullah, Chien‐Chih Chiu, Ching‐Ming Chien, Sodio C. N. Hsu   +8 more
wiley   +1 more source