Results 41 to 50 of about 5,131 (171)

Challenges and proposed solutions in making clinical research on COVID-19 ethical: a status quo analysis across German research ethics committees

open access: yesBMC Medical Ethics, 2021
Background In the course of the COVID-19 pandemic, the biomedical research community’s attempt to focus the attention on fighting COVID-19, led to several challenges within the field of research ethics.
Alice Faust   +5 more
doaj   +1 more source

Clinical Ethicists and Medical Assistance in Dying (MAiD): Possible Roles and Challenges

open access: yesBioethics, Volume 40, Issue 3, Page 267-275, March 2026.
ABSTRACT Assisted dying (AD) presents a range of challenges for clinical ethicists (CEs) and healthcare institutions seeking to involve them in its provision. Questions regarding the legitimacy, scope, and nature of CE involvement remain underexplored in the literature.
Vanessa Finley‐Roy   +3 more
wiley   +1 more source

Beyond Context‐Transfer Effects: Attenuated Familiarity During Virtual Reality‐Based Retrieval Across Different Encoding Modalities

open access: yesEuropean Journal of Neuroscience, Volume 63, Issue 5, March 2026.
The study examined potential context‐transfer effects on the relative contributions of familiarity and recollection to retrieval across virtual reality (VR) and desktop (PC) encoding conditions. Item and source memory were tested in a source memory paradigm employed in VR.
Joanna Kisker   +3 more
wiley   +1 more source

Intra‐subtype heterogeneity shapes treatment response in KMT2A‐rearranged ALL across all age groups

open access: yesHemaSphere, Volume 10, Issue 2, February 2026.
Abstract KMT2A‐rearranged B‐cell acute lymphoblastic leukemia (KMT2Ar B‐ALL) exhibits significant heterogeneity in age of onset, developmental origins, and clinical outcomes. The interplay of individual factors influencing early treatment response within this high‐risk molecular subtype remains poorly elucidated.
Alina M. Hartmann   +29 more
wiley   +1 more source

Complexation of Anthocyanin‐Rich Blackberry Extract With Ozonated Sodium Alginate: Structural, Rheological, and Color Insights

open access: yesJournal of Food Science, Volume 91, Issue 2, February 2026.
ABSTRACT Anthocyanins, valued for their health‐promoting properties and their role as natural pigments, are highly susceptible to degradation, highlighting the need for strategies to improve their stability. Biopolymer‐based systems are an alternative for interacting with and safeguarding these bioactive compounds.
Camila Yamashita   +7 more
wiley   +1 more source

A Randomized Phase 1 Study Comparing the PK, PD, Safety, and Immunogenicity of Proposed Biosimilar RGB‐14‐X and Denosumab in Healthy Adult Males

open access: yesClinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Denosumab is a monoclonal antibody targeting the receptor activator of nuclear factor kappa‐b ligand widely used for the prevention of skeletal‐related events in patients with bone metastases. This Phase 1 randomized, double‐blind, two‐arm, parallel‐group study assessed the equivalence in pharmacokinetics (PK) and compared the pharmacodynamics
Emmanuel Biver   +11 more
wiley   +1 more source

Bildung und das Ethos der Transformation

open access: yesZeitschrift für Praktische Philosophie, 2019
Thema dieses Essays sind Fragen nach dem Verhältnis theoriegeleiteter empirischer Forschung (z. B. qualitativer und quantitativer empirischer Bildungsforschung) und systematischer Analyse, Rekonstruktion und Bewertung von in pädagogischen ...
Johannes Drerup
doaj  

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, Volume 600, Issue 1, Page 20-38, January 2026.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Antoni Kępińskis „Informationsmetabolismus“ und Niklas Luhmanns „Autopoiesis“. Zwei Begriffe – ein Konzept?

open access: yesActa Universitatis Lodziensis: Folia Philosophica, 2016
Die Konzepte „Informationsmetabolismus“ von Antoni Kępiński und „Autopoiesis“ von Niklas Luhmann rekurrieren auf die Struktur biologischer Zellen. Beide Autoren übertragen diese biologischen Strukturen auf ihre jeweiligen Anwendungsfelder.
Florian Steger, Maximilian Schochow
doaj   +1 more source

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