Results 61 to 70 of about 104,589 (269)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

Bildung und das Ethos der Transformation

open access: yesZeitschrift für Praktische Philosophie, 2019
Thema dieses Essays sind Fragen nach dem Verhältnis theoriegeleiteter empirischer Forschung (z. B. qualitativer und quantitativer empirischer Bildungsforschung) und systematischer Analyse, Rekonstruktion und Bewertung von in pädagogischen ...
Johannes Drerup
doaj  

Unsolvable Riddles and the Truth of Skepticism: Wittgenstein and Cavell

open access: yesEuropean Journal of Philosophy, Volume 33, Issue 4, Page 1540-1556, December 2025.
Abstract Both Wittgenstein and Cavell see riddles as a model of intellectual difficulty. By drawing attention to it, they remind us that not all of our intellectual challenges take the form of empirically answerable questions—there may be cases of our not merely lacking knowledge, but of being caught in the fantasy that a certain type of knowledge can ...
Gilad Nir
wiley   +1 more source

Methodology and Applications of Christian Leadership Ethics [PDF]

open access: yes, 2018
A fundamental methodology for Christian leadership ethics will be proposed, which has long been pending in the discourse on ethical leadership. It is necessary to first clarify what characterizes leadership ethics, and secondly, what Christian leadership
Kreuer, Ellen, Nass, Elmar
core   +2 more sources

Eine Perspektive zu interdisziplinären Ansätzen in der Chemotaxis(forschung)

open access: yesAngewandte Chemie, Volume 137, Issue 47, November 17, 2025.
Chemotaxis ist die Bewegung individueller Agenten hin zu oder weg von einem chemischen Stimulus. Dieses Phänomen wird in den verschiedensten Fachbereichen untersucht, von Biologie hin zu Physik und auch im Ingenieurwesen. Dieses Perspektivpapier zielt darauf ab, neue Entwicklungen im Feld darzustellen und die Vereinheitlichung von Terminologie zu ...
Juliane Simmchen   +18 more
wiley   +1 more source

Statt Sterbehilfe Therapie zur Schmerzlinderung : die Grenzen der Ethik und der Wille der Patienten ; [Rezension] [PDF]

open access: yes, 2007
Rezension zu: Stephan Sahm : Sterbebegleitung und Patientenverfügung. Ärztliches Handeln an den Grenzen von Ethik und Recht ; Verlag Campus, Frankfurt 2006, ISBN 9783593381794, 265 Seiten, 32,90 ...
Bentele, Katrin
core  

TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging

open access: yesJournal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT Torquetenovirus (TTV) is a prevalent virus whose clinical significance remains unclear, potentially linked to immunosenescence. This study examines TTV species in relation to immune impairment, inflammation, and cellular stress response in aging.
Federica Novazzi   +35 more
wiley   +1 more source

Zum Umgang mit "kulturellen Fragen" in der klinischen Ethik am Beispiel der Hymenrekonstruktion [PDF]

open access: yes, 2018
Zusammenfassung: Dieser Beitrag diskutiert "kulturelle Fragen" in klinischer Ethik am Beispiel der Hymenrekonstruktion. Zunächst werden drei grundsätzliche Argumente genannt: 1) Wenn "kultur-sensitive" Themen in klinischer Ethik explizit als solche ...
Wild, Verina
core  

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

open access: yesClinical Pharmacology in Drug Development, Volume 14, Issue 10, Page 742-753, October 2025.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano   +8 more
wiley   +1 more source

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