Results 91 to 100 of about 826,642 (304)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

From Insurgency to Bureaucracy: Free Aceh Movement, Aceh Party and the New Face of Conflict

open access: yesStability : International Journal of Security and Development, 2012
The settling of the 32-year Aceh conflict not only transformed former members of the Free Aceh Movement (GAM) into administrators, constructing a new circle of elites, but also created opportunities and new spaces for economic and socio-political ...
Mohammad Hasan Ansori
doaj   +1 more source

The political economy of ethnicity [PDF]

open access: yes
The paper investigates the effects of ethnic diversity on economic performance and the risk of violent conflict. Diversity has various detrimental microeconomic effects, tending to reduce public sector performance, increase patronage, and lower the level
Paul Collier
core  

Ethnic conflict and economic disparity: Serbians and Albanians in Kosovo [PDF]

open access: yes, 2005
We use the Living Standards Measurement Study (LSMS) household survey from postconflict Kosovo to examine economic deprivation among Serbs and Albanians.
Altonji   +23 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The Predicament of Ethnic Federal System

open access: yesAfrican Journal of Political Science
The paper inquiries into ethnic federalism in lights of ethnic conflict and federal constitutional viability. It raises the basic question why some ethnic federations are successful in regulating ethnic relations while others are not.
Yohannes Getahun
doaj   +1 more source

SOCIAL ECONOMIC CHANGE AS A PRECONDITION OF ETHNIC CONFLICTS: THE CASES OF OSH CONFLICTS IN 1990 AND 2010

open access: yesVestnik MGIMO-Universiteta, 2017
This article demonstrates that ethnicity itself didn’t play a significant role to cause conflicts in Osh in 1990 and 2010, but was rather a side effect or a catalyst produced inevitably by political struggle in the country.
K. Hyunjung
doaj   +1 more source

Disarming fears of diversity : ethnic heterogeneity and state militarization, 1988-2002 [PDF]

open access: yes
The authors address the question of state militarization under conditions of ethnic and other diversity."Primordialist"claims about ancient hatreds, fear, and insecurity in such societies would lead one to expect that fractionalization, polarization, and
de Soysa, Indra, Neumayer, Eric
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Preventing inter-ethnic conflict: Evidence from the Gereb traditional institutions in Northeast Ethiopia

open access: yesEthiopian Journal of the Social Sciences and Humanities
A review of major literature on conflict prevention reveals a lack of consensus on the subject matter. One strand of the debate revolves around whether conflict prevention should be limited solely to the early and non-escalatory stages of conflict, or it
Awet Halefom Kahsay
doaj   +1 more source

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