Results 51 to 60 of about 826,642 (304)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Resolusi konflik berbasis budaya Tionghoa dan Jawa di Surakarta
Jurnal Civics: Media Kajian Kewarganegaraan, 2020 Upaya resolusi konflik dibangun untuk mencegah timbulnya konflik komunal di antara warga etnis Tionghoa dan etnis Jawa. Tujuan penelitian ini yaitu untuk menguraikan upaya dalam membangun kerukunan antara etnis Tionghoa dan etnis Jawa di Kampung Pecinan,
Annisa Istiqomah, Delfiyan Widiyanto
doaj +1 more source
Ethnonationalist Triads: Assessing the Influence of Kin Groups on Civil Wars [PDF]
, 2009 Although the case-based literature suggests that kin groups are prominent in ethnonationalist conflicts, quantitative studies of civil war onset have both overaggregated and underaggregated the role of ethnicity, by looking at civil war at the country ...
Cederman, Lars-Erik +2 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Decentralization and Ethnic Conflict: The Role of Empowerment [PDF]
Decentralization is increasing in all parts of the world. Assessing the efficiency of decentralization as a means to mitigate ethnic conflict is then of primarily importance.
Tranchant, Jean-Pierre
core +4 more sources
Ethnic Fractionalization, Ethnic Polarization, and Potential Conflict in Parent Districts of IKN
Jurnal Ilmu Sosial dan HumanioraThe purpose of this research is to determine the degree of ethnic fractionalization and polarization in the parent districts of the new Indonesian Capital of Nusantara (IKN), namely Kutai Kartanegara (Kukar) and North Penajam Paser (PPU) Districts, and ...
I Ketut Gunawan
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
‘Living’ wage, class conflict and ethnic strife [PDF]
We examine how group-specific differences in reservation wage, arising due to asymmetries in social entitlements, impact on distribution via the joint determination of class conflict between workers and employers, and ‘ethnic’ conflict among workers.
Indraneel Dasgupta
core +3 more sources