Results 71 to 80 of about 829,648 (303)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Kebijakan Peraturan Daerah Berbasis Politik Rekognisi dan Resolusi Konflik Etnik

open access: yesInformasi, 2012
Indonesia, as a multicultural country, has a high potential of conflicts among forming elements of its multiculturalism. To minimize potential of conflicts, it is necessary to construct space of co-existence for several identities.
Suharno suharno
doaj   +1 more source

Civil War, Ethnicity, and the Migration of Skilled Labor [PDF]

open access: yes
We investigate the impact of civil war on high skilled emigration rates to the OECD over the period 1985-2000. Controlling for economic and institutional characteristics of source countries, we find that civil war increases high skilled emigration by ...
Aniruddha Mitra, James T. Bang
core  

A Note on Poverty in Kosovo [PDF]

open access: yes, 2005
Kosovo is a war-torn corner of the former Yugoslavia, where a civil war between ethnic Albanians and ethnic Serbs raged during most of the 1990s. We examine the incidence and depth of poverty and some of its correlates in post-conflict Kosovo using the ...
Bhaumik, Sumon Kumar   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Ethnic Diversity and Ethnic Strife: An Interdisciplinary Perspective [PDF]

open access: yes
The objective of this paper is to present an overview of ethnicity, ethnic strife and its consequences, as seen from the perspective of the disciplines of economics, political science, social anthropology and sociology.
Kanbur, Ravi   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

MAJOR THEORETICAL APPROACHES TO CONSTRUCTIVE CONFLICT RESOLUTION IN THE NORTH CAUCASUS

open access: yesPolitologija, 2017
This article explores the major approaches to the study of conflict resolution strategy from a variety of interdisciplinary perspectives. It argues that conflict resolution strategy, as a civil integration resource, is a necessary tool for overcoming ...
Maxim Popov
doaj   +1 more source

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