Results 51 to 60 of about 155,829 (259)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Introduction: Racial and Ethnic Conflict and Violence

open access: yesInternational Journal of Conflict and Violence, 2009
Racial and ethnic violence takes many forms. Genocides, ethnic cleansing, pogroms, civil wars, and violent separatist movements are the most obvious and extreme expressions, but less organized violence such as rioting, and hate crimes by individuals or ...
Werner Bergmann, Robert D. Crutchfield
doaj   +3 more sources

Ethnic conflicts in the former Yugoslavia

open access: yesRUDN journal of Sociology, 2015
At the end of the XXth century the communist regimes in the Central and Eastern Europe collapsed, as well as the socialist system and the Warsaw Treaty’s Organization.
V A Annikova, M Radusinovich
doaj  

THE COMPLEX INTERPLAY BETWEEN CHINA’S ETHNIC CONFLICTS, NATIONAL SECURITY AND GRAND STRATEGY

open access: yesJournal of International Studies
The relationship between internal conflicts and national strategic decision-making remains complex and often unclear. This article examines the case of Xinjiang to explore the intricate connections between ethnic conflicts, national security, and China ...
Jiaxin Han   +2 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Trans-Border Ethnic Groups and Conflict Dynamics in Africa: An Evaluation of Bakongo in DRC and Angola

open access: yesİmgelem
This study examines how artificial borders drawn during the colonial period in Africa transformed the spatial distribution of ethnic groups and laid the groundwork for political conflicts involving transboundary ethnic groups.
Hande Sapmaz
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Youths’ Perception of the Impact of Inter and Intra Ethnic Conflicts on Socio-economic Development in Delta State, Nigeria

open access: yesJournal of Agricultural Extension, 2009
The study was undertaken to determine youth’s perception of the impact of ethnic conflicts on socio-economic development in Delta state. Data for the study were collected from 102 youths from Ijaw, Itsekiri and Urhobo through the use of structured ...
A R Ajayi, O M Akinnagbe, T Aghojare
doaj   +4 more sources

Ethnic identity and socio-linguistic: Multi-ethnic conflicts in Kazakhstan

open access: yesRevista de Paz y Conflictos, 2015
Kazakhstan Republic is the ninth biggest country in territorial extension and it is also an important communication link between Eastern and Western countries because of its situation.
Antonio Manuel Lozano Martín   +1 more
doaj  

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