Results 61 to 70 of about 103,457 (263)

Race, ethnicity, culture, and science [PDF]

BMJ, 1994
Race and ethnicity are commonly used variables in medical research. Each year about 2500 papers are indexed under the headings “ethnic groups” or “racial stocks” on Medline1; many more control for ethnic group or cultural differences during analysis. Patterns of disease, response to treatment, and the use of services are increasingly being explained in
K J, McKenzie, N S, Crowcroft
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Elulood Läti etniliste kultuuride uurimises: liivlaste ja mustlaste lood [PDF]

Mäetagused, 2014
Even though narrating is a universal phenomenon, there is no one universal narration model, much less a universal life story model. This is also verified by the life stories from various ethnic groups that have long lived among Latvians in the Latvian ...
Ieva Garda-Rozenberga, Māra Zirnīte
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A review of safety risk management and optimization strategies for physical education classes in Chinese schools in heat-stress environments

Frontiers in Public Health
Global warming influences rising temperatures, making outdoor physical education classes progressively challenging to organize. While heat acclimatization is essential for athletic development, the conventional emphasis on “endurance” training in Chinese
Jiaxin Li, Jiaxin Li, Yiwu Yang, Mingang Guo, Mingang Guo, Jingfei Wang   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Local Agency in Crop Booms and Busts: Insights from the Walnut Plantations of Southwest China

Mountain Research and Development
Crop boom-and-bust cycles driven by agricultural commercialization trigger dramatic agrarian change in mountain areas. There is extensive literature considering the impact of short-term crop cycles on local communities, revealing the vulnerability of ...
Weijia Zhou, Jun He
doaj   +1 more source

Ethnic and cultural diversity in Europe: validating measures of ethnic and cultural background [PDF]

Journal of Ethnic and Migration Studies, 2019
ABSTRACTSocio-cultural and ethnic origin can be a powerful predictor of social attitudes and behaviours but, unlike the situation in the classical countries of immigration such as Australia, Canada...
Schneider, SL, Heath, AF
openaire   +1 more source