Results 91 to 100 of about 13,235,717 (359)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

On archaeological definition of ethnic group: continued

open access: yesПоволжская археология, 2015
The author aimed to examine the core matter of the discussion, which has been going for a while in academic publications and numerous conferences in the Volga-Ural region.
Iskander L. Izmailov
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Le jeu des identités ou la plasticité du lexème « intégration »

open access: yesLa Bretagne Linguistique, 1998
This article looks at the way in which individuals express their identity both in terms of abstract, even mythical, stability and, at the same time, in terms of the multiple variations that each individual allows himself thanks, no doubt, to these ...
Khadiyatoulah Fall
doaj   +1 more source

Ethnobotany of the Monpa ethnic group at Arunachal Pradesh, India

open access: yesJournal of Ethnobiology and Ethnomedicine, 2011
BackgroundThe present paper documents the uses of plants in traditional herbal medicine for human and veterinary ailments, and those used for dietary supplements, religious purpose, local beverage, and plants used to poison fish and wild animals ...
Nima D Namsa   +3 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Forest Germans: a forgotten ethnic group in the contemporary landscape of the Polish Carpathians

open access: yesMiscellanea Geographica: Regional Studies on Development
In the 1340s, the Kingdom of Poland expanded eastwards, prompting large-scale settlement in the Wisłoka and Wisłok river basins, formerly a borderland between Poland and Ruthenia. This initiative integrated German and Polish settlers, who became known as
Kołpak Piotr   +3 more
doaj   +1 more source

Association of HLA-DQ trans-heterodimers with prevalence of type 1 diabetes mellitus in Buryat ethnic group

open access: yesСахарный диабет, 2012
Aims. Search for the most pronounced HLA II markers of type 1 diabetes mellitus (T1DM) in Buryat ethnic group and analysis ofHLA-DQ trans-heterodimers. Materials and methods.
Olga Nikolaevna Ivanova   +2 more
doaj   +1 more source

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