Results 91 to 100 of about 14,570,539 (400)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
[Review of] Susan Olzak. The Dynamics of Ethnic Competition and Conflict [PDF]
, 1994 Susan Olzak’s work, The Dynamics of Ethnic Competition and Conflict, is informative and contributes to an understanding of ethnic violence from an historical perspective.
Hood, David L.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Exploring Ethnic Inequalities in Admission to Russell Group Universities
Sociology, 2015 This article analyses national university applications and admissions data to explore why ethnic minority applicants to Russell Group universities are less likely to receive offers of admission than comparably qualified white applicants.
V. Boliver
semanticscholar +1 more source
Young children's cognitive achievement: home learning environment, language and ethnic background [PDF]
, 2013 For decades, research has shown differences in cognitive assessment scores between White and minority ethnic group(s) learners as well as differences across different minority ethnic groups.
Beals DE +17 more
core +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Empresários e intelectuais: agentes culturais e valorização de um grupo étnico
Ciências Sociais Unisinos, 2014 The article aims to investigate an identity process of promotion of an ethnic group by focusing in the 1970s and 1980s, since this period is characterized by a process of mod- ernization of the economy in the region of Caxias Sul, in Rio Grande do Sul ...
Maria Clara Mocellin
doaj
Management of Health System for Ethnic Minorities [PDF]
The concept of ethnic minority refers to a different ethnic group, living in a residential country, with a different birth place and ethnic membership, different language, religion and citizenship, and different culture.
Cristina Teodora NEAGU
core
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Age and Ethnic Variations in Attitudes Towards Older Persons, Family and Filial Obligations [PDF]
, 1993 Two major interpretations have been advanced to explain the frequent finding that ethnic elders have more extensive kin support networks than Anglo elders. Structural interpretations argue that the exigencies of poverty and ill health cause minorities to
Ortega, Suzanne T., Shafer, John
core +1 more source