Trends in hepatocellular carcinoma stage by racial/ethnic group in the United States, 1992-2019. [PDF]
JHEP Rep, 2023 Alvarez CS +4 more
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Multiculturalism of Bishkek city: ethnicity and language in soviet and post-soviet times
Народы и религии Евразии, 2018 The paper studies the changes in the ethnic composition of Bishkek city in the pre-Soviet period, Soviet and the post-Soviet periods, and the factors that contributed to the creation and development of multiethnic society in Bishkek city. The other focus
Чолпон Дженишбековна Чотаева
doaj
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Oral health of an indigenous population in northeastern Brazil: a cross-sectional Study of the Fulni-ô ethnic group. [PDF]
Sao Paulo Med J, 2023 Koike BDV +9 more
europepmc +1 more source
Psychiatry and ethnic groups [PDF]
British Journal of Psychiatry, 1990 K, Lloyd, P, Moodley
openaire +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Intergenerational trauma and war-induced PTSD in Kosovo: insights from the Albanian ethnic group. [PDF]
Front Psychol, 2023 Hyseni Duraku Z, Jahiu G, Geci D.
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Wild edible plants and their cultural significance among the Zhuang ethnic group in Fangchenggang, Guangxi, China. [PDF]
J Ethnobiol Ethnomed, 2023 Liu S +6 more
europepmc +1 more source