Results 211 to 220 of about 14,292,945 (405)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

The Prevalence of Glaucoma in the Jirel Ethnic Group of Nepal. [PDF]

open access: yesFront Ophthalmol (Lausanne), 2022
Miller S   +9 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

THE ROLE AND PLACE OF TRADITIONAL SOCIAL INSTITUTES IN THE TIME OF SOCIAL MODERNIZATION IN RUSSIA IN THE EARLY 21st CENTURY

open access: yesRUDN Journal of Public Administration, 2015
The article is devoted to the problem of interaction and mutual influence between modernization processes in contemporary Russian society and traditional social institutions of some Nations of Russian Federation.
Dmitry V Yurkov
doaj  

Diversity of Studies on Neighborhood Greenspace and Brain Health by Racialized/Ethnic Group and Geographic Region: A Rapid Review. [PDF]

open access: yesInt J Environ Res Public Health, 2023
Besser LM   +7 more
europepmc   +1 more source

Are Generics and Negativity about Social Groups Common on Social Media? A Comparative Analysis of Twitter (X) Data [PDF]

open access: yesarXiv
Generics (unquantified generalizations) are thought to be pervasive in communication and when they are about social groups, this may offend and polarize people because generics gloss over variations between individuals. Generics about social groups might be particularly common on Twitter (X). This remains unexplored, however. Using machine learning (ML)
arxiv  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy