A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Inequalities in colorectal cancer diagnosis by ethnic group: a population-level study in the English National Health Service. [PDF]
Birch RJ +7 more
europepmc +1 more source
Rate of Nutrition-Related Chronic Diseases Among a Multi-Ethnic Group of Uninsured Adults. [PDF]
Ajabshir S +5 more
europepmc +1 more source
Mother–Infant Interactions in Early Head Start: A Person-Oriented Within-Ethnic Group Approach
C. Brady-Smith +6 more
semanticscholar +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Restorativeness mediates the effect of a brief virtual reality mindfulness exposure with a multi-ethnic group in a natural environment on global identity salience: a pilot study with adolescents. [PDF]
Russo C +6 more
europepmc +1 more source
Group Dynamics and Allocation of Advanced Heart Failure Therapies-Heart Transplants and Ventricular Assist Devices-By Gender, Racial, and Ethnic Group. [PDF]
Breathett K +13 more
europepmc +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Correction: Restorativeness mediates the effect of a brief virtual reality mindfulness exposure with a multi-ethnic group in a natural environment on global identity salience: a pilot study with adolescents. [PDF]
Russo C +6 more
europepmc +1 more source

