Autosomal Recessive Juvenile Parkinsonism Maps to 6q25.2-q27 in Four Ethnic Groups: Detailed Genetic Mapping of the Linked Region [PDF]
Alison C. Jones+10 more
openalex +1 more source
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Reference intervals of hematological parameters in the Chilean adult population and the Mapuche ethnic group. [PDF]
Letelier PJ+5 more
europepmc +1 more source
Rate of Nutrition-Related Chronic Diseases Among a Multi-Ethnic Group of Uninsured Adults. [PDF]
Ajabshir S+5 more
europepmc +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Inequalities in colorectal cancer diagnosis by ethnic group: a population-level study in the English National Health Service. [PDF]
Birch RJ+7 more
europepmc +1 more source
A multimodal strategy to improve race/ethnic group equity in administration of neutralizing monoclonal antibody treatment for COVID-19 outpatients. [PDF]
Fish LE+7 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Cultural practices, healthcare-seeking behaviors, and wildlife interface: Zoonotic disease risks among the Phu Thai Ethnic Group in Thailand. [PDF]
Bubpa N+8 more
europepmc +1 more source