Results 51 to 60 of about 416,755 (262)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
IS THE BALKANIZATION OF THE UKRAINIAN-RUSSIAN CONFLICT PROBABLE?
Russian Journal of Economics and Law, 2015 Objective: to determine the possibility and probability of Balkanization of the Ukrainian-Russian inter-societal relations.Methods: the need to study the main factors affecting the state of the modern Russian-Ukrainian conflict in its ethno-political ...
A. P. Koshkin, V. V. Cherdantsev
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The role of light in regulating plant growth, development and sugar metabolism: a review
Frontiers in Plant ScienceLight provides the necessary energy for plant photosynthesis, which allows plants to produce organic matter and energy conversion, during plant growth and development.
Wenyuan Wu +10 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
La etica en la investigación: el caso con los tule (kunas) de Urabá, Colombia.
Biomédica: revista del Instituto Nacional de Salud, 2006 La investigación Cultura, alimentación y malaria entre los tule (kuna) se realizó en el resguardo de Caimán Nuevo, Urabá antioqueño, Colombia, y buscó analizar la prevalencia de la malaria y sus relaciones con la hipovitaminosis A y el estado nutricional,
Gloria Alcaraz, Adriana Correa
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Empresários e intelectuais: agentes culturais e valorização de um grupo étnico
Ciências Sociais Unisinos, 2014 The article aims to investigate an identity process of promotion of an ethnic group by focusing in the 1970s and 1980s, since this period is characterized by a process of mod- ernization of the economy in the region of Caxias Sul, in Rio Grande do Sul ...
Maria Clara Mocellin
doaj